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The Outcome of Severe Acute Schizophrenic Illnesses After One Year

Published online by Cambridge University Press:  29 January 2018

Eve C. Johnstone
Affiliation:
Department of Psychiatry, Northwick Park Hospital and Clinical Research Centre, Watford Road, Harrow, Middlesex, HA1 3UJ
C. D. Frith
Affiliation:
Department of Psychiatry, Northwick Park Hospital and Clinical Research Centre, Watford Road, Harrow, Middlesex, HA1 3UJ
Aviva Gold
Affiliation:
Department of Psychiatry, Northwick Park Hospital and Clinical Research Centre, Watford Road, Harrow, Middlesex, HA1 3UJ
Marilyn Stevens
Affiliation:
Department of Psychiatry, Northwick Park Hospital and Clinical Research Centre, Watford Road, Harrow, Middlesex, HA1 3UJ

Summary

Forty-five patients with acute schizophrenic illnesses (defined by PSE criteria) were assessed in clinical, cognitive and social terms before being entered in a four week study of the isomers of flupenthixol and placebo. At the end of one year they were re-assessed in the same terms. The clinical and psychological features of the acute illness and the drug treatment given did not predict outcome. Poor outcome in social terms was significantly related to severe social isolation in the initial assessment and to the presence of nuclear symptoms and negative schizophrenic features at follow-up.

Type
Research Article
Copyright
Copyright © The Royal College of Psychiatrists 

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