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Serum Immunoglobulins and Cognitive Status in the Elderly: 1. A Population Study

Published online by Cambridge University Press:  29 January 2018

Donna Cohen  and
Carl Eisdorfer
Donna Cohen
Affiliation:
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington 98195, U.S.A.
Carl Eisdorfer
Affiliation:
Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington 98195, U.S.A.
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Summary

Fifty-seven cognitively impaired elderly had significantly elevated serum IgG (P $0.005) and IgA (P $0.01) levels and similar IgM levels, compared to a population of 65 elderly matched for age and sex, who did not manifest cognitive impairment. These findings are compatible with a current hypothesis that immunological factors may be important in the cognitive disorders observed with increasing frequency among the aged.

Type
Papers
Information
The British Journal of Psychiatry , Volume 136 , Issue 1 , January 1980 , pp. 33 - 39
Copyright
Copyright © The Royal College of Psychiatrists 

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