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Effect of Electroconvulsive Therapy on Erythrocyte Adenosine Triphosphatase Activity in Depressive Illness

Published online by Cambridge University Press:  29 January 2018

L. J. Whalley
Affiliation:
MRC Brain Metabolism Unit, Thomas Clouston Clinic, 153, Morningside Drive, Edinburgh EH10 5LG
M. Scott
Affiliation:
MRC Brain Metabolism Unit, Thomas Clouston Clinic, 153, Morningside Drive, Edinburgh EH10 5LG
H. W. Reading
Affiliation:
MRC Brain Metabolism Unit, Thomas Clouston Clinic, 153, Morningside Drive, Edinburgh EH10 5LG
J. E. Christie
Affiliation:
MRC Brain Metabolism Unit, Thomas Clouston Clinic, 153, Morningside Drive, Edinburgh EH10 5LG

Summary

Erythrocyte membrane adenosine triphosphatase activities were examined in twelve unipolar depressed patients receiving ECT. Eleven patients undergoing diagnostic cystoscopy served as controls for the acute effects of anaesthesia, and sixteen healthy subjects served as non-depressed controls. The unipolar depressed patients had a slight reduction in their (Na++K+)-ATPase activity but effective ECT treatment was not associated with any increase in this activity. This approach is unlikely to cast further light on the membrane phenomenology of depressive illness.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1980 

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