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Clinical State, Plasma Levels of Haloperidol and Prolactin: A Correlation Study in Chronic Schizophrenia

Published online by Cambridge University Press:  29 January 2018

V. A. Rama Rao ,
Margaret Bishop  and
Alec Coppen
V. A. Rama Rao
Affiliation:
All Saints' Hospital, Chatham, Kent, and Guy's Hospital Medical School, London SE1
Margaret Bishop
Affiliation:
MRC Neuropsychiatry Laboratory, West Park Hospital, Epsom, Surrey KT19 8PB
Alec Coppen
Affiliation:
MRC Neuropsychiatry Laboratory, West Park Hospital, Epsom, Surrey KT19 8PB
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Summary

Chronic schizophrenic patients were maintained for six months on a dosage of haloperidol adjusted to give optimum clinical effect. A correlation was found between extrapyramidal symptoms and prolactin levels and also between plasma haloperidol concentration and plasma prolactin levels. Estimation of plasma prolactin would be a reliable measurement of patients' compliance with medication.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 137 , Issue 6 , December 1980 , pp. 518 - 521
Copyright
Copyright © Royal College of Psychiatrists, 1980 

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