Hostname: page-component-76fb5796d-skm99 Total loading time: 0 Render date: 2024-04-26T01:02:10.704Z Has data issue: false hasContentIssue false
  • English
  • Français

Normal Ventricles in Young Schizophrenics

Published online by Cambridge University Press:  29 January 2018

Francine Benes ,
Pearson Sunderland ,
Barry D. Jones ,
Marjorie J. LeMay ,
Bruce M. Cohen  and
Joseph F. Lipinski
Francine Benes
Affiliation:
McLean Hospital, 115 Mill Street, Belmont, Mass. 02178, USA
Pearson Sunderland
Affiliation:
McLean Hospital
Barry D. Jones
Affiliation:
Mailman Research Center, McLean Hospital
Marjorie J. LeMay
Affiliation:
Massachusetts General Hospital, Harvard Medical School
Bruce M. Cohen
Affiliation:
Clinical Biochemistry Laboratory, Mailman Research Center, McLean Hospital; Harvard Medical School
Joseph F. Lipinski
Affiliation:
Clinical Research Section, Mailman Research Center, McLean Hospital; Harvard Medical School
Get access Rights & Permissions [Opens in a new window]

Summary

The CT scans of 11 schizophrenics and 26 controls were evaluated for both linear (Evan's and cella media ratios) and volume (planimetry and grid ratios) measurements of ventricular size. There were no differences between the two groups on any of the measures obtained. These results are discussed in relation to previous reports showing ventricular enlargement in schizophrenics. The relatively younger age and briefer period of hospitalization in this present sample are suggested as variables possibly associated with these findings.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 141 , Issue 1 , July 1982 , pp. 90 - 93
Copyright
Copyright © The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Barron, M. D., Jacobs, L. & Kinkel, W. R. (1976) Changes in size of normal lateral ventricles during aging determined by computerized tomography. Neurology, 26, 1011–13.CrossRefGoogle ScholarPubMed
Feighner, J. P., Robins, E. & Guze, S. (1972) Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry, 26, 57–63.CrossRefGoogle ScholarPubMed
Golden, C. J., Moses, J., Zelazowski, R., Graber, B., Zatz, L., Horvath, T. & Berger, P. (1980) Cerebral ventricular size and neuropsychological impairment in young schizophrenics. Archives of General Psychiatry, 37, 619–23.CrossRefGoogle Scholar
Haug, J. (1962) Pneumoencephalographic studies in mental disease. Acta Psychiatrica Scandinavica, 38, (Suppl. 165), 66–86.Google ScholarPubMed
Haug, J. (1977) Age and sex dependence of the size of normal ventricles on computed tomography. Neuroradiology, 14, 201–4.CrossRefGoogle ScholarPubMed
Johnstone, E. C., Crow, T. J., Firth, C. D., Husband, J. & Kreel, L. (1976) Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet, ii, 924–6.Google Scholar
Lancet (1980) Schizophrenia and cerebral atrophy, i, 858–9.Google Scholar
Penn, R. D., Belanger, M. & Yasnoff, W. (1978) Ventricular volume in man computed from CT scans. Annals of Neurology, 3, 216–23.CrossRefGoogle Scholar
Pope, H. G. & Lipinski, J. F. (1978) Diagnosis in schizophrenia and manic-depressive illness: A reassessment of the specificity of ‘schizophrenic’ symptoms in light of current research. Archives of General Psychiatry, 35, 811–28.CrossRefGoogle ScholarPubMed
Storey, P. B. (1966) Lumbar air encephalography in chronic schizophrenia: A controlled experiment. British Journal of Psychiatry, 112, 135–44.CrossRefGoogle ScholarPubMed
Synek, V., Reuben, J. R. & du Boulay, G. H. (1976) Comparing Evan's index and computerized axial tomography in assessing relationship of ventricular size to brain size. Neurology, 26, 231–3.CrossRefGoogle ScholarPubMed
Tanaka, Y., Hazama, H., Kawahara, R., Kobayashi, K. (1981) Computerized tomography of the brain in schizophrenic patients: A controlled study. Acta Psychiatrica Scandinavica, 63, 191–7.CrossRefGoogle ScholarPubMed
Trimble, L. & Kingsley, D. (1978) Cerebral ventricular size in chronic schizophrenia. Lancet, i, 278–9.Google Scholar
Weibel, E. R. & Bolender, R. P. (1973) Stereological techniques for electron microscopic morphometry. In Principles and Techniques of Electron Microscopy. Vol III (ed. Hayat, M. S.). New York: Van Nostrand Reinhold.Google Scholar
Weinberger, D. R., Bigelow, L., Kleinman, J., Klein, S., Rosenblatt, J. & Wyatt, J. (1980) Cerebral ventricular enlargement in chronic schizophrenia. Archives of General Psychiatry, 37, 11–13.CrossRefGoogle ScholarPubMed
Weinberger, D. R., de Lisi, L. E., Neophytides, A. N. & Wyatt, R. J. (1981) Familial aspects of CT scan abnormalities in chronic schizophrenic patients. Psychiatry Research, 4, 65–71.CrossRefGoogle ScholarPubMed
Weinberger, D. R., Torrey, E. F., Neophytides, A. & Wyatt, R. (1979) Lateral cerebral ventricular enlargement in chronic schizophrenia. Archives of General Psychiatry, 36, 735–9.CrossRefGoogle ScholarPubMed
Weinstein, M. R. (1954) Histopathological changes in the brain in schizophrenia. A critical review. Archives of Neurology and Psychiatry, 71, 539–53.Google ScholarPubMed
Submit a response

eLetters

No eLetters have been published for this article.