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The Asymmetric Lateralization of Tactile Extinction in Schizophrenia: the Possible Role of Limbic and Frontal Regions

Published online by Cambridge University Press:  29 January 2018

Silvio Scarone ,
Elisabetta Pieri ,
Orsola Gambini ,
Roberto Massironi  and
Carlo L. Cazzullo
Silvio Scarone
Affiliation:
Department of Psychiatry, Milan Medical School, Via GF Besta 1, 20161 Milano, Italy
Elisabetta Pieri
Affiliation:
Department of Psychiatry, Milan Medical School, Via GF Besta 1, 20161 Milano, Italy
Orsola Gambini
Affiliation:
Department of Psychiatry, Milan Medical School, Via GF Besta 1, 20161 Milano, Italy
Roberto Massironi
Affiliation:
Department of Psychiatry, Milan Medical School, Via GF Besta 1, 20161 Milano, Italy
Carlo L. Cazzullo
Affiliation:
Department of Psychiatry, Milan Medical School, Via GF Besta 1, 20161 Milano, Italy
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Summary

This study evaluates the tactile extinction rate in acute and chronic schizophrenics by means of the Quality Extinction Test (QET) proposed by Schwartz in 1977. This procedure is successful in detecting ipsilateral abnormal extinction rates in neurological patients with dominant frontal lesions. Sixty schizophrenics and sixty controls were tested. The results suggest adominant temporo-parietal dysfunction in acute patients and a dominant frontal dysfunction in chronic patients.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 141 , Issue 4 , October 1982 , pp. 350 - 353
Copyright
Copyright © Royal College of Psychiatrists, 1982 

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References

Carr, S. A. (1980) Interhemispheric transfer of stereognosic information in chronic schizophrenia. British Journal of Psychiatry, 136, 53–8.CrossRefGoogle Scholar
Eaton, E. M., Busk, J., Maloney, M. P., Sloane, B. R., Wipple, K. & White, K. (1979) Hemispheric dysfunction in schizophrenia: assessment by visual perception tasks. Psychiatry Research, 1, 325–32.CrossRefGoogle ScholarPubMed
Giannitrapani, D. & Kayton, L. (1974) Schizophrenia and EEG spectral analysis. Electroencephalography and Clinical Neurophysiology, 36, 377–86.CrossRefGoogle ScholarPubMed
Gruzelier, J. H. (1981) Cerebral laterality and psychopathology: fact and fiction. Psychological Medicine, 11, 219–27.Google Scholar
Gur, R. E. (1978) Left hemisphere dysfunction and left hemisphere overactivation in schizophrenia. Journal of Abnormal Psychology, 87, 226–38.CrossRefGoogle ScholarPubMed
Ingvar, D. H. (1980) Abnormal distribution of cerebral activity in chronic schizophrenia: a neurophysiological interpretation. In Perspective in Schizophrenia Research, (eds. Baxter, C. and Melnechuk, T.). New York: Raven Press.Google Scholar
Itil, T. M., Hsu, W., Saletu, B. & Mednick, S. (1974) Computer EEG and evoked potentials in children of high risk for schizophrenia. American Journal of Psychiatry, 131, 892–900.CrossRefGoogle ScholarPubMed
Johnstone, E. C., Crown, T. J., Frith, C. D., Husband, J. & Kreel, L. (1976) Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet, 2, 924–5.Google ScholarPubMed
Naeser, M. A., Levine, H. L., Benson, F., Stuss, D. T. & Weir, W. S. (1981) Frontal leucotomy size and hemispheric asymmetries of computerized tomography scans of schizophrenics with variable recovery. Archives of Neurology, 38, 30–7.CrossRefGoogle ScholarPubMed
Nauta, W. J. H. (1971) The problem of the frontal lobe: a reinterpretation. Journal of Psychiatric Research, 8, 167–87.CrossRefGoogle ScholarPubMed
Raczkowski, D., Kalat, J. W. & Nebes, R. (1974) Reliability and validity of some handedness questionnaire items. Neuropsychologia, 12, 43–8.CrossRefGoogle ScholarPubMed
Rosenthal, R. & Bigelow, L. B. (1972) Quantitative brain measurement in chronic schizophrenia. British Journal of Psychiatry, 121, 259–64.CrossRefGoogle ScholarPubMed
Scarone, S., Garavaglia, P. F. & Cazzullo, C. L. (1981) Further evidence of dominant hemisphere dysfunction in chronic schizophrenia. British Journal of Psychiatry, 138, 354–5.CrossRefGoogle ScholarPubMed
Schwartz, A. S., Marchok, P. L. & Flynn, R. E. (1977) A sensitive test for tactile extinction: results in patients with parietal and frontal lobe disease. Journal of Neurology, Neurosurgery and Psychiatry, 40, 228–33.CrossRefGoogle ScholarPubMed
Schwartz, A. S., Marchok, P. L., Kreinick, C. J. & Flynn, R. E. (1979) The asymmetric lateralization of tactile extinction in patients with unilateral cerebral dysfunction. Brain, 102, 669–84.CrossRefGoogle ScholarPubMed
Spitzer, R. L., Endicott, J. & Robins, E. (1975) Clinical criteria for psychiatric disorders and DSM-III. American Journal of Psychiatry, 132, 1187–92.Google ScholarPubMed
Stevens, J. R., Bigelow, L., Denney, D., Lipkin, J., Livermore, A. H., Rauscher, F. & Wyatt, R. J. (1979) Telemetered EEG-EOG during psychotic behaviours of schizophrenia. Archives of General Psychiatry, 36, 251–62.CrossRefGoogle ScholarPubMed
Taylor, M. A., Greenspan, B. & Abrams, R. (1979) (1979) Lateralized neuropsychological dysfunction in affective disorder and schizophrenia. American Journal of Psychiatry, 136, 1031–4.Google Scholar
Venables, P. H. (1980) Primary dysfunction and cortical lateralization in schizophrenia. In Functional States of the Brain: Their Determinants, (eds. Koukkou, M., Lehmann, D. and Angst, J.). Elsevier, North Holland: Biomedical Press.Google Scholar
Walker, H. A. & Birch, G. H. (1979) Lateral preference and right-left awareness in schizophrenic children. Journal of Nervous and Mental Diseases, 151, 341–51.Google Scholar
Weinberger, D. R. & Wyatt, R. J. (1980) Structural brain abnormalities in chronic schizophrenia: Computed tomography findings. In Perspective in Schizophrenia Research, (eds. Baxter, C. and Melnechuk, T.). New York: Raven Press.Google Scholar
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