Hostname: page-component-76fb5796d-25wd4 Total loading time: 0 Render date: 2024-04-26T03:57:44.601Z Has data issue: false hasContentIssue false

Lithium withdrawal Trial in Chronic Schizophrenia

Published online by Cambridge University Press:  29 January 2018

N. J. Delva
Affiliation:
Department of Psychiatry, Queen's University, Kingston, Ontario, Canada
F. J. J. Letemendia
Affiliation:
Department of Psychiatry, Queen's University, Kingston, Ontario, Canada
A. W. Prowse
Affiliation:
Department of Psychiatry, Queen's University, Kingston, Ontario, Canada

Summary

Six schizophrenic patients treated with lithium and neuroleptics for at least two years had their lithium medication stopped. Two patients relapsed within two weeks, and four did not after one year of follow-up.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1982 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

American Psychiatric Association (1980) Diagnostic and Statistical Manual of Mental Disorders, (Third edition). Washington: American Psychiatric Association.Google Scholar
Biederman, J., Lerner, Y. & Belmaker, R. H. (1979) Combination of lithium carbonate and haloperidol in schizo-affective disorder. Archives of General Psychiatry, 36, 327–33.Google Scholar
Delva, N. J. & Letemendia, F. J. J. (1982) Lithium treatment in schizophrenia and schizo-affective disorders. British Journal of Psychiatry, 141, 387400.CrossRefGoogle ScholarPubMed
Feighner, J. P., Robins, E., Guze, S. G., Woodruff, R. A. Jr., Winokur, G. & Munoz, R. (1972) Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry, 26, 5763.CrossRefGoogle ScholarPubMed
Hestbech, J., Hansen, H. E., Amdisen, A. & Olson, S. (1977) Chronic renal lesions following long-term treatment with lithium. Kidney International, 12, 205–13.CrossRefGoogle ScholarPubMed
Pert, A., Rosenblatt, J. E., Sivit, C., Pert, C. B. & Bunney, W. E. Jr. (1978) Long-term treatment with lithium prevents the development of dopamine receptor supersensitivity. Science, 201, 171–3.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.