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Use of Renal Enzymes to Evaluate Nephrotoxicity in Lithium Treated Patients

Published online by Cambridge University Press:  29 January 2018

Michael J. Garvey ,
V. B. Tuason ,
Charles H. Blomquist  and
Sutaeg Hwang
Michael J. Garvey
Affiliation:
Department of Psychiatry
V. B. Tuason
Affiliation:
Department of Psychiatry
Charles H. Blomquist
Affiliation:
Department of Obstetrics and Gynecology
Sutaeg Hwang
Affiliation:
Department of Psychiatry University of Minnesota, St Paul-Ramsey Medical Center, 640 Jackson Street, St Paul, Minnesota 55101, USA
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Summary

N-acetyl-β-glucosaminadase (NAG) is a renal enzyme which is an early, sensitive and reliable indicator of renal damage. NAG assays of midstream spot urines were not significantly different in a group of controls when compared to patients starting lithium for the first time, or to a group of patients who had been taking lithium for more than one year. However, a small number of lithium-treated patients may have evidence of renal damage, identifiable by NAG assay.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 141 , Issue 4 , October 1982 , pp. 420 - 422
Copyright
Copyright © Royal College of Psychiatrists, 1982 

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