Hostname: page-component-8448b6f56d-t5pn6 Total loading time: 0 Render date: 2024-04-23T13:26:56.962Z Has data issue: false hasContentIssue false
  • English
  • Français

Family History Study of Anorexia Nervosa and Bulimia

Published online by Cambridge University Press:  29 January 2018

James I. Hudson ,
Harrison G. Pope Jr ,
Jeffrey M. Jonas  and
Deborah Yurgelun-Todd
Get access Rights & Permissions [Opens in a new window]

Summary

The 420 first-degree relatives of 14 patients with anorexia nervosa, 55 patients with bulimia, and 20 patients with both disorders were evaluated for the presence of psychiatric illness, using DSM-III criteria, by the family history method. The morbid risk for affective disorder in the families of the eating disorder probands was similar to that found in the families of patients with bipolar disorder; but was significantly greater than that found in the families of patients with schizophrenia or borderline personality disorder. These results add to the growing evidence that anorexia nervosa and bulimia are closely related to affective disorder.

Type
Papers
Information
The British Journal of Psychiatry , Volume 142 , Issue 2 , February 1983 , pp. 133 - 137
Copyright
Copyright © 1983 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

American Psychiatric Association. (1980) DSM-III: Diagnostic and Statistical Manual of Mental Disorders. (Third edition). Washington, DC: American Psychiatric Association.Google Scholar
Andreason, N. C., Endicott, J., Spitzer, R. L. & Winokur, G. (1977) The family history method using diagnostic criteria. Archives of General Psychiatry, 34, 1229–35.Google Scholar
Boyar, R. M., Hellman, L. D., Roffward, H. P., Katz, J., Zumoff, B., O'Connor, J., Bradlow, H. D. & Fukushima, D. K. (1977) Cortisol secretion and metabolism in anorexia nervosa. New England Journal of Medicine, 296, 190–3.Google Scholar
Cantwell, D. P., Sturzenberger, S., Burroughs, J., Salkin, B. & Green, J. D. (1977) Anorexia nervosa: an affective disorder? Archives of General Psychiatry, 34, 1087–93.Google Scholar
Carroll, B. F. Feinberg, M., Groden, J. F., Tarika, J., Albala, A. A., Haskett, R. F., James, N. M., Kronfol, Z., Lohr, N., Steiner, M., de Vigne, J. P. & Young, E. (1981) A specific laboratory test for the diagnosis of melancholia: standardization, validation, and clinical utility. Archives of General Psychiatry, 38, 15–22.Google Scholar
Casper, R. C., Eckert, E. D., Halmi, K. A., Goldberg, S. C. & Davis, J. M. (1980) Bulimia: its incidence and clinical importance in patients with anorexia nervosa. Archives of General Psychiatry, 37, 1030–35.Google Scholar
Crisp, A. H., Hsu, L. K. G., Harding, B. & Hartshorn, J. (1980) Clinical features of anorexia nervosa. Journal of Psychosomatic Research, 24, 179–91.CrossRefGoogle ScholarPubMed
Eckert, E. D., Goldberg, S. C., Halmi, K. A., Casper, R. C. & Davis, J. M. (1982) Depression in anorexia nervosa. Psychological Medicine, 12, 115–22.CrossRefGoogle ScholarPubMed
Feighner, J. P., Robins, E., Guze, S. B., Woodruff, R. A., Winokur, G. & Munoz, R. (1972) Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry, 26, 57–63.Google Scholar
Folstein, M. F., Wakeling, A & DeSouza, V. (1977) Analogue scale measurement of the symptoms of patients suffering from anorexia nervosa. in Anorexia Nervosa (ed. R. A. Vigersky). New York: Raven Press.Google Scholar
Garfinkel, P. E., Moldofsky, H. & Garner, D. M. (1980) The heterogeneity of anorexia nervosa: bulimia as a distinct subgroup. Archives of General Psychiatry, 37, 1036–40.CrossRefGoogle ScholarPubMed
Gerner, R. H. & Gwirtsman, H. E. (1981) Abnormalities of dexamethasone suppression test and urinary MHPG in anorexia nervosa. American Journal of Psychiatary, 138, 652–3.Google Scholar
Gershon, E. S., Hamovit, J. R., Schreiber, J. L., Dibble, E. D., Kaye, W., Nurnberger, J. I. Jr., Andersen, A. & Ebert, M. (1982) Anorexia nervosa and major affective disorders associated in families. Paper presented at the Annual Meeting of the American Psychopathological Association, March 1, 1982, New York.Google Scholar
Gross, H. A., Ebert, M. H., Faden, V. B., Goldberg, S. C., Nee, L. E. & Kaye, W. H. (1981) A double-blind controlled trial of lithium carbonate in primary anorexia nervosa. Journal of Clinical Psychopharmacology, 1, 376–81.Google Scholar
Hudson, J. I., Laffer, P. S. & Pope, H. G. Jr. (1982) Bulimia related to affective disorder by family history and response to the dexamethasone suppression test. American Journal of Psychiatry, 137, 695–7.Google Scholar
Hsu, L. K. G., Crisp, A. H. & Harding, B. (1979) Outcome of anorexia nervosa. Lancet, i, 61–5.Google Scholar
Jonas, J. M., Hudson, J. I. & Pope, H. G. Jr. Treatment of bulimia with monoamine oxidase inhibitors. Journal of Clinical Psychopharmacology, in press.Google Scholar
Mendlewicz, J., Fleiss, J. L., Cataldo, M. & Rainer, J. D. (1975) Accuracy of the family history method in affective illness. Archives of General Psychiatry, 32, 309–14.Google Scholar
Mills, I. H. (1976) Amitriptyline therapy in anorexia nervosa. Lancet, 2, 687.Google Scholar
Morgan, H. G. & Russell, G. F. M. (1975) Value of family background in clinical features as predictors of long-term outcome in anorexia nervosa: four-year follow-up study of 41 patients. Psychological Medicine, 5, 355–71.CrossRefGoogle ScholarPubMed
Needleman, H. L. & Waber, D. (1976) Amitriptyline therapy in patients with anorexia nervosa. Lancet, 2, 580.CrossRefGoogle ScholarPubMed
Nogami, Y. & Yabana, F. (1977) On kibarashi-gui (binge-eating). Folia Psychiatrica et Neurologica Japonica, 31, 159–66.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.