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Depression and the Newcastle Scale

Their Relationship to the Dexamethasone Suppression Test

Published online by Cambridge University Press:  29 January 2018

Neil L. Holden*
Affiliation:
Department of Psychiatry, The Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP

Summary

The results of 41 standardised dexamethasone suppression tests (DST) with the Newcastle Scale diagnostic weighting for endogenous depression correlated significantly (P <.001). Specificity of the DST was found to be 89 per cent, sensitivity 82 per cent and the diagnostic confidence for endogenous depression 94 per cent. This strongly supports the validity of the Newcastle Scale diagnostic weighting for endogenous depression.

Type
Research Article
Copyright
Copyright © 1983 The Royal College of Psychiatrists 

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References

Carney, M. W. P., Roth, M. & Garside, R. F. (1965) The diagnosis of depressive syndromes and the prediction of ECT response. British Journal of Psychiatry, 111, 659–74.CrossRefGoogle Scholar
Carney, M. W. P., Sheffield, B. F. (1972) Depression and the Newcastle Scales: Their relationship to Hamilton's Scale. British Journal of Psychiatry, 121, 3540.CrossRefGoogle ScholarPubMed
Carroll, B. J., Feinberg, M., Greden, J. F. et al (1981) A specific laboratory test for the diagnosis of melancholia: Standardisation, validation and clinical utility. Archives of General Psychiatry, 38, 1522.CrossRefGoogle ScholarPubMed
Carroll, B. J. (1982) The dexamethasone suppression test for melancholia. British Journal of Psychiatry, 140, 292304.CrossRefGoogle ScholarPubMed
Ettigi, P. G. & Brown, G. M. (1977) Psychoneuroendocrinology of affective disorder: An overview. The American Journal of Psychiatry, 134, 493501.Google ScholarPubMed
Feinberg, M. & Carroll, B. J. (1982) Separation of subtypes of depression using discriminant analysis. I. Separation of unipolar endogenous depression from non-endogenous depression. British Journal of Psychiatry, 140, 384–91.CrossRefGoogle ScholarPubMed
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