The British Journal of Psychiatry
Comparison of the prophylactic action of flupenthixol with placebo in lithium treated manic-depressive patients.
J Esparon, J Kolloori, G J Naylor, A M McHarg, A H Smith, S E Hopwood

Abstract

A double-blind cross-over trial of depot flupenthixol in recurrent manic depressive psychosis was carried out. All patients continued on lithium. Eleven patients completed the two-year trial. Flupenthixol appeared to have no prophylactic effect.