Hostname: page-component-8448b6f56d-jr42d Total loading time: 0 Render date: 2024-04-23T10:36:00.409Z Has data issue: false hasContentIssue false
  • English
  • Français

Computed Tomographic Density Numbers

A Comparative Study of Patients with Senile Dementia and Normal Elderly Controls

Published online by Cambridge University Press:  29 January 2018

J. Colgan ,
M. Naguib  and
R. Levy
J. Colgan
Affiliation:
King's College Hospital, London
M. Naguib
Affiliation:
The Maudsley Hospital, London
R. Levy*
Affiliation:
Section of Old Age Psychiatry
*
Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SES 8AF, UK.
Get access Rights & Permissions [Opens in a new window]

Abstract

Cranial computed tomography (CT) scans of 48 patients with senile dementia of the Alzheimer type (SDAT) and 40 normal elderly volunteers were compared. The demented group were found to have significantly larger lateral ventricles assessed planimetrically and by using a linear measure of the ratio of the maximum width of the frontal horns of the lateral ventricles to the maximum intracranial diameter. Attenuation density was computed for 1 5 brain regions. The demented group did not differ significantly from the normal controls with respect to attenuation density In any of the regions studied.

Type
Papers
Information
The British Journal of Psychiatry , Volume 149 , Issue 6 , December 1986 , pp. 716 - 719
Copyright
Copyright © 1986 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Present address: Senior Lecturer and Honorary Consultant Psychiatrist, St CharlesHospital, London W10

References

Bondareff, W., Baldy, R. & Levy, R.(1981) Quantitative computed tomography in senile dementia. Archives of General Psychiatry, 38, 1365–1368.Google Scholar
Brinkman, S. D., Sarwar, M., Levin, H. S. & Morris, H. H. III.(1981) Quantitative indexes of computed tomography in dementia and normal aging. Radiology, 138, 89–92.Google Scholar
Colgan, J.(1985) Regional density and survival in senile dementia-an interim report on a prospective computed tomography study. British Journal of Psychiatry, 147, 63–66.Google Scholar
Copeland, J. R., Kelleher, M. J., Kellett, J. M. et al (1976) A semi-structured clinical interview for the assessment of diagnosis and mental state in the elderly: the geriatric mental state schedule 1. Development and reliability. Psychological Medicine, 6, 439–449.CrossRefGoogle Scholar
Di Chiro, C., Brooks, R. A., Dubal, L. & Chew, E.(1978) The apical artefact: elevated attenuation values towards the apex of the skull. Journal of Computer Assisted Tomography, 2, 65–70.Google Scholar
Gado, M., Hughes, C. P., Danzjger, W. et al (1982) Volumetric measurements in cerebrospinal fluid spaces in demented subjects and controls. Radiology, 144, 535–538.Google Scholar
Gado, M., Hughes, C. P., Danzjger, W., Danziger, W., Chi, D. et al (1983) Brain parenchymal density measurements by CT in demented subjects and normal controls. Radiology, 147, 703–710.Google Scholar
George, A. E., de Leon, M. J., Ferris, S. H. & Kricheff, L. L. (1981) Parenchymal CT correlates of senile dementia (Alzheimer disease): Loss of gray white matter discriminability. American Journal of Neuroradiology, 2, 205–213.Google Scholar
Hodkinson, H. M.(1973) Mental impairment in the elderly. Journal of the Royal College of Physicians, 7, 305–317.Google ScholarPubMed
Jacoby, R. & Levy, R.(1980) Computed tomography in the elderly: 2 Senile dementia: diagnosis and functional impairment. British Journal of Psychiatry, 136, 256–269.Google Scholar
Jacoby, R. & Levy, R. & Dawson, J.(1980) Computed tomography in the elderly: 1 The normal population. British Journal of Psychiatry, 136, 249–255.Google Scholar
Kendrick, D. C.(1965) Speed and learning in the diagnosis of diffuse brain change in elderly subjects; A Bayesian statistical approach. British Journal of Clinical and Social Psychology, 4, 141–148.Google Scholar
De Leon, M. J. & George, A. E.(1983) Computed tomography in aging and dementia of the Alzheimer type. In Advances in Neurology Vol. 38 (eds R. Mayeux and W. Rosen). New York: Raven Press.Google Scholar
De Leon, M. J. & George, A. E., Ferris, S. H., George, A. E. et al (1980) Computed tomography evaluations of brain-behaviour relationships in senile dementia of the Alzheimer's type. Neurobiology of Aging, 1, 69–79.Google Scholar
Næser, M. A., Albert, M. S. & Kleeeield, J.(1982) New methods in the CT scan diagnosing of Alzheimer's disease: examination of white and gray matter mean CT density numbers. In Alzheimer's disease: a report of progress. Aging, Vol. 19 (eds S. Corkin et at). New York: Raven Press.Google Scholar
Naguib, M. & Levy, R.(1982) Prediction of outcome in senile dementia-a computed tomographic study. British Journal of Psychiatry, 140, 263–267.Google Scholar
Wilson, R., Fox, J., Huckman, M. et al (1982) Computed tomography in dementia. Neurology, 32, 1054–1057.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.