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Cognitive Functioning in Parkinson's Disease: in Relation to Prevalence of Dementia and Psychiatric Diagnosis

Published online by Cambridge University Press:  29 January 2018

J. R. Oyebode*
Affiliation:
Newcastle Health Authority
W. A. Barker
Affiliation:
Department of Psychiatry, University of Newcastle-upon-Tyne
G. Blessed
Affiliation:
Brighton Clinic, Newcastle General Hospital
D. J. Dick
Affiliation:
Regional Neurology Centre, Newcastle
P. G. Britton
Affiliation:
Department of Psychiatry, University of Newcastle-upon-Tyne
*
Newcastle General Hospital, Newcastle-upon-Tyne NE4 6BE, UK

Abstract

Forty-three neurologically and psychiatrically assessed patients with idiopathic Parkinson's disease (PD) underwent detailed cognitive assessment. Cognitive deficits typical of senile dementia of Alzheimer's type (SDAT) were found in 7% but the majority showed definite impairments not typical of SDAT. Cognitive impairment was significantly more likely in those with more severe PD symptoms. There was substantial agreement between psychiatric diagnosis and psychological picture of SDAT and some links were found between other diagnostic categories and nature of cognitive functioning. However, cognitive deficits were also found In two-thirds of patients with no psychiatric diagnosis.

Type
Papers
Copyright
Copyright © 1986 The Royal College of Psychiatrists 

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References

American Psychiatric Association (1980) Diagnostic and Statistical Manual of Mental Disorders (3rd ed.) DSM-III. Washington DC: Division of Public Affairs, APA.Google Scholar
Benton, A. L.(1968) Differential behavioural effects of frontal lobe disease. Neuropsyekologia, 6, 5360.CrossRefGoogle Scholar
Boller, F.(1980) Mental status of patients with Parkinson's disease. Journal of Clinical Neuropsychology, 2, 157172.CrossRefGoogle Scholar
Brown, R. G. & Marsden, C. D.(1984) How common is dementia in Parkinson's disease? Lancet, 2, 12621265.CrossRefGoogle ScholarPubMed
Kay, D. W. K., Bergmann, K., Foster, E. M., McKechnie, A. A. & Roth, M.(1970) Mental illness and hospital usage in the elderly: a random sample followed up. Comprehensive Psychiatry, 11, 2635.CrossRefGoogle ScholarPubMed
Lees, A. J.(1985) Parkinson's disease and dementia, Lancet, i, 4344.CrossRefGoogle Scholar
Lees, A. J. & Smith, E.(1983) Cognitive deficits in the early stages of Parkinson's disease. Brain, 106, 257270.CrossRefGoogle ScholarPubMed
Mayeux, R.(1982) Depression and dementia in Parkinson's disease. In Butterworths International Medical Reviews, Neurology 2: Movement Disorders (eds C. D. Marsden & S. Fahr). London: Butterworth Scientific.Google Scholar
McCarthy, R., Gresty, M. & Findley, L. J.(1985) Parkinson's disease and dementia. Lancet, i, 407.CrossRefGoogle Scholar
Morris, R., Wheatley, J. R. & Britton, P. G.(1983) Retrieval from long-term memory in senile dementia: Cued recall revisited, British Journal of Clinical Psychology, 72, 141142.CrossRefGoogle Scholar
Nelson, H. E. & O'Connell, A.(1978) Dementia: the estimation of premorbid intelligence levels using the New Adult Reading Test. Cortex, 14, 234244.CrossRefGoogle ScholarPubMed
Patrick, H. T. & Levy, D. M.(1922) Parkinson's disease: A clinical study of 146 cases. Archives of Neurology and Psychiatry, 7. 711720.CrossRefGoogle Scholar
Pattie, A. H. & Gilleard, C.(1979) Clifton Assessment Procedures for the Elderly (CAPE), Sevenoaks: Hodder & Stoughton.Google Scholar
Perry, E. K., Curtis, M., Dick, D. J., Candy, J. M., Atack, J. R., Bloxham, C. A., Blessed, G., Fairbairn, A., Tomlinson, B. E. & Perry, R. H. (1985) Cholinergic correlates of cognitive impairment in Parkinson's disease: comparisons with Alzheimer's disease. Journal of Neurology, Neurosurgery and Psychiatry, 48, 413421.CrossRefGoogle ScholarPubMed
Raven, S. C., Court, J. H. & Raven, J.(1977) Manual for Raven's Progressive Vocabulary Scales, London: H. K. Lewis.Google Scholar
Taylor, A., Saint-Cyr, J. A. & Lang, A. E.(1985) Dementia prevalence in Parkinson's disease. Lancet, I, 1037.CrossRefGoogle Scholar
Terman, L. M. & Merrill, M. A.(1973) Manual for Stafford' Binet Intelligence Scale. Third Revision.Google Scholar
Webster, D. D.(1968) Critical analysis of the disability of Parkinson's disease. Modem Treatment, 5, 257282.Google Scholar
Wechsler, D.(1958) The Measurement and Appraisal of Adult Intelligence, 4th ed, Baltimore: Williams & Wilkins.Google Scholar
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