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Spectrum Concept of Neuroleptic Malignant Syndrome

Published online by Cambridge University Press:  02 January 2018

Adityanjec ,
Suarn Singh ,
Gurnam Singh  and
Susan Ong
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Abstract

Although neuroleptic malignant syndrome (NMS) was initially thought to be a rare, idiosyncratic complication, the incidence estimates have been rising over the years. A part of this increase can be explained on the basis of an over-inclusive definition of NMS. The unitary concept of NMS has been challenged recently and a spectrum concept has been enunciated on the basis of findings of retrospective chart-reviews which have used too broad a definition of NMS. The authors describe three cases of neuroleptic-related toxicity with different clinical presentations which appeared in a manner apparently supporting the spectrum concept. They discuss this controversial concept critically, however, and caution against its overzealous use in routine clinical practice owing to its far-reaching clinical implications.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 153 , Issue 1 , July 1988 , pp. 107 - 111
Copyright
Copyright © Royal College of Psychiatrists, 1988 

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