Hostname: page-component-8448b6f56d-mp689 Total loading time: 0 Render date: 2024-04-18T04:27:38.852Z Has data issue: false hasContentIssue false
  • English
  • Français

In Reply … A Locus Closer to the Telomere?

Published online by Cambridge University Press:  02 January 2018

T. J. Crow ,
L. E. DeLisi  and
E. C. Johnstone
T. J. Crow*
Affiliation:
Division of Psychiatry, Clinical Research Centre, Northwick Park Hospital, Harrow HA1 3UJ
L. E. DeLisi
Affiliation:
Department of Psychiatry, State University of New York at Stony Brook, New York, 11756, USA
E. C. Johnstone
Affiliation:
Division of Psychiatry, Clinical Research Centre, Northwick Park Hospital, Harrow HA1 3UJ
*
∗Correspondence
Get access Rights & Permissions [Opens in a new window]

Extract

Curtis & Gurling quote with approval Sturt & Shur's (1985) critique of same-sex concordance with the implication that the phenomenon has been explained as ascertainment bias. While some of Sturt & Shur's points are valid, we note that these are not relevant to those series of dizygotic (DZ) twins that, by including both concordant and discordant pairs, controlled for sampling bias. In these series a same-sex excess in concordant pairs is present and substantial (Table II of our paper (Crow et al, 1989)).

Type
Points of View
Information
The British Journal of Psychiatry , Volume 156 , Issue 3 , March 1990 , pp. 416 - 420
Copyright
Copyright © Royal College of Psychiatrists, 1990 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Collinge, J., et al (1989) Evidence for a pseudo-autosomal locus for schizophrenia: a sibling pair analysis. Cytogenetics and Cell Genetics, 51, 978.Google Scholar
Crow, T. J., DeLisi, L. E. & Johnstone, E. C. (1989) Concordance by sex in sibling pairs is paternally inherited: evidence for a pseudoautosomal locus. British Journal of Psychiatry, 155, 92–97.Google Scholar
Lewine, R. J. J. (1988) Gender and schizophrenia. In Handbook of Schizophrenia, Vol. 3 (ed. Tsuang, M. T. & Simpson, J. C.), pp. 379–397. Amsterdam: Elsevier.Google Scholar
Penrose, L. S. (1942) Auxiliary genes for determining sex as contributory causes of mental illness. Journal of Mental Science, 88, 308–316.CrossRefGoogle Scholar
Rosenthal, D. (1962) Familial concordance by sex with respect to schizophrenia. Psychological Bulletin, 59, 401–421.Google Scholar
Schulz, B. (1932) Zur Erbpathologie der Schizophrenic. Zeitschrift fur die Gesammte Neurologie und Psychiatric, 143, 175–293.Google Scholar
Sturt, E. & Shur, E. (1985) Sex concordance for schizophrenia in proband-relative pairs. British Journal of Psychiatry, 147, 44–47.Google Scholar
Suarez, B. K. & van Eerdewegh, P. (1984) A comparison of three affected sib-pair scoring methods to detect HLA-linked disease susceptibility genes. American Journal of Medical Genetics, 18, 135–146.Google Scholar
Tsuang, M. T. (1967) A study of pairs of siblings both hospitalised for mental disorder. British Journal of Psychiatry, 113, 283–300.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.