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Is Parental Age Related to the Risk of Alzheimer's Disease?

Published online by Cambridge University Press:  02 January 2018

Albert Hofman ,
Cornelia M. Van Duijn ,
Willem Schulte ,
Theunis A. Tanja ,
Robert Haaxma ,
Arie J. Lameris  and
Rolf J. Saan
Albert Hofman*
Affiliation:
Department of Epidemiology and Biostatistics, Erasmus University Medical School, PO Box 1738, 3000 DR Rotterdam, The Netherlands
*
∗Correspondence
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Extract

Advanced maternal and paternal age were investigated as putative risk factors for AD in 198 clinically diagnosed Alzheimer patients and in 198 randomly selected healthy controls. No significant differences in average age of fathers and of mothers at birth of the subject were observed. The risk of AD was not significantly different across categories of maternal and paternal age. The association with parental age was not different for sporadic and familial AD. These findings do not support the view of a maternal or paternal age effect on AD.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 157 , Issue 2 , August 1990 , pp. 273 - 275
Copyright
Copyright © Royal College of Psychiatrists, 1990 

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