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Structure and Function in Neurology and Psychiatry

Published online by Cambridge University Press:  02 January 2018

E. H. Reynolds
E. H. Reynolds*
Affiliation:
Maudsley and Kings College Hospitals, Denmark Hill, London SE5 9RS
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Abstract

In the 19th century the triumphs of neuropathology and the clinico-anatomical method led to the evolution of neurology as a separate ‘organically’ based discipline associated with the concept of functional localisation. At the same time the growth of psychodynamic psychiatry contributed to the progressive separation of the two disciplines, with neuropsychiatry sitting uneasily in the middle. Psychiatrists are now showing increasing interest in the structure and function of the nervous system, but are having difficulty in integrating their findings into ‘functional’ diseases. This may be because disorder of function in the nervous system is much more complex than previously envisaged. The function of the nervous system is profoundly affected by psychological and social factors. The view that neurology is wholly ‘organic’ and synonymous with structural disease of the nervous system is fallacious. Neurological patients have complex dynamic disorders of function in the nervous system whether or not structural disease is present.

Type
Lecture
Information
The British Journal of Psychiatry , Volume 157 , Issue 4 , October 1990 , pp. 481 - 490
Copyright
Copyright © Royal College of Psychiatrists, 1990 

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References

Andreasen, N. C. (ed.) (1986) Can Schizophrenia be Localized in the Brain? Washington, DC: American Psychiatric Press.Google Scholar
Andreasen, N. C., Nasrallah, H. A., Dunn, V., et al (1986) Structural abnormalities in the frontal system in schizophrenia: a magnetic resonance imaging study. Archives of General Psychiatry, 43, 136–144.Google Scholar
Bennett, E., Diamond, M. C., Krech, D., et al (1964) Chemical and anatomic plasticity of the brain. Science, 146, 610.Google Scholar
Berman, K. F., Zec, R. F. & Weinberger, D. R. (1986) Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. II. Role of neuroleptic treatment, attention, and mental effort. Archives of General Psychiatry, 43, 126–135.Google Scholar
Blakemore, C. & Cooper, G. F. (1970) Development of the brain depends on the visual environment. Nature, 228, 477–478.CrossRefGoogle ScholarPubMed
Broca, P. (1865) Sur la faculte du langage articule. Paris Bulletin Societie Anthropologic, 6, 337–393.Google Scholar
Cheyne, G. (1733) The English Malady: or, A Treatise of Nervous Diseases of all Kinds, as Spleen, Vapours, Lowness of Spirits, Hypochondriacal and Hysterical Distempers. London: Strahan & Leake.Google Scholar
Clarke, E. & Jacyna, L. S. (1987) 19th Century Origins of Neuroscientific Concepts. Berkeley: University of California Press.Google Scholar
Crow, T. J. (1980) Molecular pathology of schizophrenia: more than one disease process. British Medical Journal, 280, 66–68.CrossRefGoogle ScholarPubMed
Cullen, W. (1769) Apparatus ad Nosologiam Methodicam, seu Synopsis Nosologiae Methodicae in Usum Studiosorum. Edinburgh: Creech.Google Scholar
Cullen, W. (1777) First Lines of the Practice of Phsyic. Edinburgh: Creech.Google Scholar
Delgado, J. M. R. (1967) Aggression and defense under cerebral radio control. In Aggression and Defense, Neural Mechanisms and Social Patterns (eds C. D. Clemente & D. Lindsley). UCLA Forum in Medical Science, no. 7, vol. V., pp. 171–193. Berkeley: University of California Press.CrossRefGoogle ScholarPubMed
Delgado, J. M. R. & Mir, D. (1969) Fragmental organization of emotional behaviour in the monkey brain. Annals of the New York Academy of Science, 159, 731–751.CrossRefGoogle ScholarPubMed
DeLisi, L. E., Goldin, L. R. Hamovit, J. R., et al (1986) A family study of the association of increased ventricular size with schizophrenia. Archives of General Psychiatry, 43, 148–153.Google Scholar
Elwes, R. D. C., Johnson, A. L., Shorvon, S. D., et al (1984) The prognosis for seizure control in newly diagnosed epilepsy. New England Journal of Medicine, 311, 944–947.Google Scholar
Elwes, R. D. C., Johnson, A. L. & Reynolds, E. H. (1988) The course of untreated epilepsy. British Medical Journal, 297, 948–950.Google Scholar
Farmer, A., Jackson, R., McGuffin, P., et al (1987) Cerebral ventricular enlargement in chronic schizophrenia: consistencies and contradictions. British Journal of Psychiatry, 150, 324–330.Google Scholar
Ferrier, D. (1878) The Localisation of Cerebral Disease. London: Smith, Elder & Co.Google Scholar
Freud, S. (1891) Zur Auffassung der Aphasien. Wien. (Authorised translation with an introduction by Stengel, E. (1953) London: Imago Publishing Company).Google Scholar
Goddard, G. V. (1967) Development of epileptic seizures through brain stimulation at low intensity. Nature, 214, 1020–1021.Google Scholar
Gowers, W. R. (1881) Epilepsy and Other Chronic Convulsive Disorders: Their Causes, Symptoms and Treatment. London: Churchill.Google Scholar
Gowers, W. R. (1886) Manual of Disorders of the Nervous System. London: Churchill.Google Scholar
Grunbaum, A. S. F. & Sherrington, C. S. (1901) Observations on physiology of the cerebral cortex of some of the higher apes. Proceedings of the Royal Society, London, 69, 206.Google Scholar
Grunbaum, A. S. F. & Sherrington, C. S. (1903) Observations on physiology of the cerebral cortex of anthropoid apes. Proceedings of the Royal Society, London, 72, 152.Google Scholar
Harlow, H. F., Harlow, M. K. & Suomi, S. J. (1971) From thought to therapy; lessons from a primate laboratory. How investigation of the learning capability of rhesus monkeys has led to the study of their behavioural abnormalities and rehabilitation. American Science, 59, 538–549.Google Scholar
Harrington, A. (1987) Medicine, Mind and the Double Brain. Princeton: Princeton University Press.Google Scholar
Hill, D. (1964) The bridge between neurology and psychiatry. Lancet, i, 509–514.Google Scholar
Jaccoud, S. (1872) Traite de Pathologie Interne (2nd edn). Paris: Delahaye.Google Scholar
Jackson, H. J. (1873) On the anatomical, physiological and pathological investigation of epilepsies. Reports of the West Riding Lunatic Asylum, 3, 315–339.Google Scholar
Jeannerod, N. (1985) The Brain Machine. Cambridge, Massachusetts: Harvard University Press.CrossRefGoogle Scholar
Johnstone, E. C., Crow, T. J., Frith, C. D., et al (1976) Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet, ii, 924–926.Google Scholar
Johnstone, E. C., Crow, T. J., Frith, C. D., et al (1978) The dementia of dementia praecox. Acta Psychiatrica Scandinavica, 57, 305–324.CrossRefGoogle ScholarPubMed
Kalakowska, T., Williams, A. O. Ardern, M., et al (1985) Schizophrenia with good and poor outcome. 1: Early clinical features, response to neuroleptics and signs of organic dysfunction. British Journal of Psychiatry, 146, 229–246.CrossRefGoogle Scholar
Kinnier Wilson, S. A. (1940) Neurology. London: Arnold.Google Scholar
Lishman, A. W. (1978) Organic Psychiatry: The Psychological Consequences of Cerebral Disorder. Oxford: Blackwell Scientific.Google Scholar
Lopez-Pinero, J. M. (1983) Historical Origins of the Concept of Neurosis (trans. Berrios, D.). Cambridge: Cambridge University Press.Google Scholar
Lorenz, K. (1970) Studies in Animal and Human Behaviour, vol. 1 (trans. Martin, R.). London: Methuen.Google Scholar
Meynert, T. (1884) Psychiatric Klinic der Erkrankungen def Vorderhirns. Vienna: W. Braumuller.Google Scholar
Morrell, F. (1969) Physiology and histochemistry of the mirror focus. In Basic Mechanisms of the Epilepsies (eds H. H. Jasper, A. A. Ward & A. Pope), pp. 357–370. Boston: Little Brown.Google Scholar
Morrell, F. (1985) Secondary epileptogenesis in man. Archives of Neurology, 41, 318–335.Google Scholar
Nasrallah, H. A., Jacoby, C. G., McCalley-Whitters, M., et al (1982) Cerebral ventricular enlargement in subtypes of chronic schizophrenia. Archives of General Psychiatry, 39, 774–777.Google Scholar
Nasrallah, H. A., Olson, S. C., McCalley-Whitters, M., et al (1986) Cerebral ventricular enlargement in schizophrenia. Archives of General Psychiatry, 43, 157–159.CrossRefGoogle ScholarPubMed
Owen, M. J., Lewis, S. W. (1986) Lateral ventricular size in schizophrenia. Lancet, ii, 223–224.Google Scholar
Owens, D. C. C., Johnstone, E. C., Crow, T. J., et al (1985) Lateral ventricular size in schizophrenia; relationship to the disease process and its clinical manifestations. Psychological Medicine, 15, 27–41.Google Scholar
Pearlson, G. D. & Veroff, A. E. (1981) Computerised tomographic scan changes in manic depressive illness. Lancet, ii, 470.Google Scholar
Penfield, W. (1958) The excitable cortex in conscious man. The Sherrington Lectures. Liverpool: Liverpool University Press.Google Scholar
Penfield, W. & Welch, K. (1949) Instability of response to stimulation of the sensorimotor cortex of man. Journal of Physiology, 109, 358–365.Google Scholar
Penfield, W. & Jasper, H. (1954) Epilepsy and the Functional Anatomy of the Human Brain. London: Churchill.Google Scholar
Pincus, J. H. & Tucker, G. J. (1985) Behavioural Neurology. Oxford: Oxford University Press.Google Scholar
Pinel, P. (1798) Nosographie Philosophique, ou la Methode de L'Analyse appliquee a la Medicine. Paris: Brosson.Google Scholar
Reveley, A. M., Reveley, M. A., Clifford, C. A., et al (1982) Cerebral ventricular size in twins discordant for schizophrenia. Lancet, i, 540–541.CrossRefGoogle ScholarPubMed
Reveley, A. M., Reveley, M. A. Murray, R. M. (1984) Cerebral ventricular enlargement in nongenetic schizophrenia; a controlled twin study. British Journal of Psychiatry, 144, 89–93.Google Scholar
Reveley, M. A. (1985) Ventricular enlargement in schizophrenia: the validity of computerised tomographic findings. British Journal of Psychiatry, 147, 233–240.Google Scholar
Reynolds, E. H. (1987) Early treatment and prognosis of epilepsy. Epilepsia, 28, 97–106.CrossRefGoogle ScholarPubMed
Reynolds, E. H. (1988) Prevention of chronic epilepsy. Epilepsia, 29 (suppl. 1), S25–S28.Google Scholar
Reynolds, E. H. (1989) The process of epilepsy. In The Clinical Relevance of Kindling (eds T. Bolwig & M. R. Trimble), pp. 149–160. Chichester: Wiley.Google Scholar
Reynolds, E. H., Elwes, R. D. C. & Shorvon, S. D. (1983) Why does epilepsy become intractable? Prevention of chronic epilepsy. Lancet, ii, 952–954.Google Scholar
Romberg, M. H. (1840–46) Lehrbuch der Nervenkrankheiten des Menschen. Berlin: Duncker.Google Scholar
Scottish Schizophrenia Research Group, MacDonald, H. L. & Best, J. J. K. (1989) The Scottish first episode schizophrenia study. VI. Computerised tomography brain scans in patients and controls. British Journal of Psychiatry, 154, 492–498.Google Scholar
Sherrington, C. S. (1941) Man on his nature. The Gifford Lectures, Edinburgh 1937–8. Cambridge: Cambridge University Press.Google Scholar
Smith, G. N. & Iacono, W. G. (1986) Lateral ventricular size in schizophrenia and choice of control group. Lancet, ii, 145.Google ScholarPubMed
Standish-Barry, H. M. A. S., Bouras, N., Bridges, P. K., et al (1982) Pneumoencephalographic and computerised axial tomography scan changes in affective disorder. British Journal of Psychiatry, 141, 614–617.Google Scholar
Trimble, M. R. (1981) Neuropsychiatry. Chichester: Wiley.Google Scholar
Trimble, M. R. (1982) Functional diseases. British Medical Journal, 285, 1768–1770.Google Scholar
Trimble, M. R. (1987) The neurology of schizophrenia. In Recurrent and Chronic Psychoses (ed. T. J. Crow). Edinburgh: Churchill Livingstone.Google Scholar
Trimble, M. R. & Reynolds, E. H. (eds) (1986) What is Epilepsy? Edinburgh: Churchill Livingstone.Google Scholar
Volkmar, F. R. & Greenough, W. J. (1972) Rearing complexity affects branching of dendrites in visual cortex of rats. Science, 176, 1445–1447.Google Scholar
Wada, J. A. (ed.) (1976) Kindling. New York: Raven Press.Google Scholar
Wada, J. A. (ed.) (1981) Kindling 2. New York: Raven Press.Google Scholar
Weinberger, D. R., Berman, K. F. & Zec, R. F. (1986) Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence. Archives of General Psychiatry, 43, 114–124.Google Scholar
Wernicke, K. (1874) Der Aphasische Symptomkomplex. Breslau: Kohn & Neigart.Google Scholar
Whytt, R. (1765) Observations on the Nature, Causes and Cure of Those Disorders Which Are Commonly Called Nervous, Hypochondriac or Hysteric. Edinburgh: Beckett & Du Hondt.Google Scholar
Wiesel, T. V. & Hubel, D. H. (1965) Extent of recovery from the effects of visual deprivation in kittens. Journal of Neurophysiology, 28, 1029–1040.Google Scholar
Williams, A. O., Reveley, M. A., Kolakowska, T., et al (1985) Schizophrenia with good and poor outcome. II. Cerebral ventricular size and its clinical significance. British Journal of Psychiatry, 146, 239–246.Google Scholar
Willis, T. (1682) Opera Omnia. Amstelodami: Wetstenius.Google Scholar
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