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A Comparison of the Withdrawal Responses of Heroin and Methadone Addicts during Detoxification

Published online by Cambridge University Press:  02 January 2018

Michael Gossop  and
John Strang
Michael Gossop
Affiliation:
Drug Dependence Clinical Research and Treatment Unit, The Bethlem Royal Hospital and The Maudsley Hospital, Beckenham, Kent BR3 3BX
John Strang
Affiliation:
Drug Dependence Clinical Research and Treatment Unit, The Bethlem Royal Hospital and The Maudsley Hospital, Beckenham, Kent BR3 3BX
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Abstract

This study compares the withdrawal responses of methadone and heroin addicts during a ten-day in-patient detoxification programme with methadone. Contrary to suggestions in the literature, the methadone group reported more severe withdrawal symptoms during both the acute withdrawal phase and the recovery phase. There were no differences between the two groups in onset or duration of symptoms. Whereas there may be reasons to favour methadone as a maintenance drug, its use may lead to difficulties during withdrawal.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 158 , Issue 5 , May 1991 , pp. 697 - 699
Copyright
Copyright © Royal College of Psychiatrists, 1991 

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References

Banks, A. & Waller, T. (1988) Drug Misuse: A Practical Handbook for GPs. Oxford: Blackwell.Google Scholar
Bradley, B., Gossop, M., Phillips, G., et al (1987) The development of an Opiate Withdrawal Scale (OWS). British Journal of Addiction, 82, 1139–1142.Google Scholar
Ghodse, A. H., Creighton, F. J. & Bhat, A. V. (1990) Comparison of oral preparations of heroin and methadone to stabilise opiate misusers as inpatients. British Medical Journal, 300, 719–720.Google Scholar
Gossop, M. (1990) The development of a short opiate withdrawal scale (SOWS). Addictive Behaviors, 15, 487–490.Google Scholar
Gossop, M., Johns, A. & Green, L. (1986) Opiate withdrawal: inpatient versus outpatient programmes and preferred versus random assignment to treatment. British Medical Journal, 293, 103–104.Google Scholar
Gossop, M., Bradley, B. & Phillips, G. (1987) An investigation of withdrawal symptoms shown by opiate addicts during and subsequent to a 21–day inpatient methadone detoxification procedure. Addictive Behaviors, 12, 1–6.Google Scholar
Gossop, M., Green, L., Phillips, G., et al (1989a) Lapse, relapse and survival among opiate addicts after treatment. British Journal of Psychiatry, 154, 348–353.CrossRefGoogle ScholarPubMed
Gossop, M., Griffiths, P., Bradley, B., et al (1989b) Opiate withdrawal symptoms in response to 10–day and 21-day methadone withdrawal programmes. British Journal of Psychiatry, 154, 360–363.Google Scholar
Hunt, D., Lipton, D., Goldsmith, D., et al (1986) “It takes your heart”: the image of methadone maintenance in the addict world and its effect on recruitment into treatment. International Journal of the Addictions, 20, 1751–1771.Google Scholar
Jaffe, J. (1985) Drug addiction and drug abuse. In The Pharmacological Basis of Therapeutics (eds A. Goodman Gilman, A. Goodman, T. Rall, et al ). New York: Macmillan.Google Scholar
Johns, A. & Gossop, M. (1985) Prescribing methadone for the opiate addict: a problem of dosage conversion. Drug and Alcohol Dependence, 16, 61–66.Google Scholar
Kleber, H., Gold, M. & Riordan, C. (1980) The use of clonidine in detoxification from opiates. United Nations Bulletin on Narcotics, 32, 1–10.Google Scholar
Robertson, R. (1987) Heroin, AIDS and Society. London: Hodder and Stoughton.Google Scholar
Royal College of Psychiatrists (1989) District–level services for drug-takers: the role of the general psychiatrist. Bulletin of the Royal College of Psychiatrists, 13, 322–325.Google Scholar
Stewart, T. (1987) The Heroin Users. Guernsey: Guernsey Press.Google Scholar
Vogel, V., Isbell, H. & Chapman, K. (1948) Present status of narcotic addiction. Journal of the American Medical Association, 138, 1019–1026.Google Scholar
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