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Changes in the Positive and Negative Symptoms of Schizophrenic In-patients in China

Published online by Cambridge University Press:  02 January 2018

Michael R. Phillips ,
Zuan Zhao ,
Xianzhang Xiong ,
Xiufang Cheng ,
Guirong Sun  and
Ningsheng Wu
Michael R. Phillips*
Affiliation:
Research Centre of Psychological Medicine, Shashi Psychiatric Hospital, Shashi, Hubei, People's Republic of China, 434000
Zuan Zhao
Affiliation:
Shashi Psychiatric Hospital, Shashi, Hubei, PRC
Xianzhang Xiong
Affiliation:
Huilong Guan Psychiatric Hospital, Beijing, PRC
Xiufang Cheng
Affiliation:
Jilin Neuropsychiatric Hospital, Siping, Jilin, PRC
Guirong Sun
Affiliation:
Nanjing Neuropsychiatric Hospital, Nanjing, Jiangsu, PRC
Ningsheng Wu
Affiliation:
Nanjing Neuropsychiatric Hospital, Nanjing, Jiangsu, PRC
*
∗Correspondence
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Abstract

Positive and negative symptoms at admission and discharge of 401 unselected schizophrenic patients from four psychiatric hospitals around China were studied. On admission, 58% of patients had prominent negative symptoms and the overall severity of negative symptoms was similar to that of positive symptoms; at discharge, negative symptoms were more prevalent and more severe. The severity of negative symptoms was not significantly correlated with duration of illness or with dosage of medication; 48% of first-episode, drug-naive patients had prominent negative symptoms on admission. Negative symptoms responded to standard neuroleptic treatment, but the improvement was less marked than that in positive symptoms (47% v. 80%). The proportion of patients classified as positive type, negative type, and mixed type schizophrenia altered dramatically with treatment. These findings highlight the importance of negative symptoms in the assessment and treatment of both acute and chronic schizophrenia.

Type
Papers
Information
The British Journal of Psychiatry , Volume 159 , Issue 2 , August 1991 , pp. 226 - 231
Copyright
Copyright © 1991 The Royal College of Psychiatrists 

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