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Trace Elements and the Electroencephalogram During Long-term Lithium Treatment

Published online by Cambridge University Press:  02 January 2018

Norman S. Harvey
Affiliation:
University of Sheffield, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF
John Jarratt
Affiliation:
Royal Hallamshire Hospital, Sheffield
Neil I. Ward
Affiliation:
Chemistry Department, University of Surrey, Guildford, Surrey

Abstract

Endogenous bromine has been found to be raised during lithium treatment, and it has been suggested that it may augment the therapeutic effect of lithium. Our findings in a study of 12 patients and 12 controls support this contention. Electroencephalographic effects of bromine, vanadium and aluminium were studied – higher bromine and vanadium levels were associated with irregular cortical activity. Electroencephalographic abnormalities were associated with more side-effects of lithium.

Type
Papers
Copyright
Copyright © The Royal College of Psychiatrists, 1992 

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