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Supersensitivity Psychosis with Concurrent Episodic Vomiting

Published online by Cambridge University Press:  02 January 2018

Katy Malcolm*
Affiliation:
University Department of Psychiatry, Northern General Hospital, Sheffield S5 7AU

Abstract

A patient with a 15-year history of psychiatric illness treated with neuroleptics presented with vomiting, thought alienation, auditory hallucinations and self-neglect. Dopaminergic supersensitivity was diagnosed and increased doses of neuroleptics caused cessation of vomiting. The patient is currently attempting discontinuation of neuroleptics.

Type
Brief Reports
Copyright
Copyright © 1992 The Royal College of Psychiatrists 

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References

American Psychiatric Association (1980) Diagnostic and Statistical Manual of Mental Disorders (3rd edn) (DSM–III). Washington, DC: APA.Google Scholar
Brand, E. D., Harris, T. D., Borison, H. L., et al (1954) The antiemetic activity of 10-(dimethylaminopropyl)-2-chlorophenothiazine (chlorpromazine) in dog and cat. Journal of Pharmacology & Experimental Therapeutics, 110, 8692.Google Scholar
Chouinard, G. & Jones, B. D. (1978) Neuroleptic induced supersensitivity psychosis. American Journal of Psychiatry, 131, 14091410.Google Scholar
Chouinard, G. & Steinberg, S. (1984) New clinical concepts of neuroleptic induced supersensitivity disorders: tardive dyskinesia and SSP. In Guidelines for the Use of Psychotropic Drugs (eds Stancer, H. C., Garfinkel, P. E. & Rakoff, V. M.), pp. 205227. New York: Spectrum Publications.CrossRefGoogle Scholar
Hunt, J. I., Singh, H., Simpson, G. M., et al (1988) Neuroleptic-induced supersensitivity psychosis: retrospective study of schizophrenic inpatients. Journal of Clinical Psychiatry, 49, 258261.Google ScholarPubMed
Schwartz, J. C., Acid, Y., Bouthenet, M.-L., et al (1986) Neurochemical investigations into the human area postrema. In Nausea and Vomiting: Mechanisms and Treatment. (eds Davis, C. J., Lake-Bakaar, G. V. & Grahame-Smith, D. G.), pp. 1830. Berlin: Springer-Verlag.CrossRefGoogle Scholar
Shen, W. W., Baig, M. S. A., Sata, L. S., et al (1983) Dopamine receptor supersensitivity and the chemo-receptor trigger zone. Biological Psychiatry, 18, 917921.Google Scholar
Steadman, T. J. & Whiteford, H. A. (1990) Dopaminergic supersensitivity and vomiting among schizophrenic patients. Acta Psychiatrica Scandinavica, 81, 9495.CrossRefGoogle Scholar
Weinberger, D. R., Bigelow, L. B., et al (1981) Drug withdrawal in chronic schizophrenic patients: in search of neuroleptic-induced supersensitivity psychosis. Journal of Clinical Psychopharmacology, 1, 120123.CrossRefGoogle ScholarPubMed
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