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Carbamazepine-Induced Systemic Lupus Erythematosus

Published online by Cambridge University Press:  02 January 2018

M. Welcker
Affiliation:
Psychiatrische Klinik, University of Munich, Nußbaumstr. 7, D-8000 Munich 2, Germany
M. Schattenkirchner
Affiliation:
Medizinische Poliklinik, University of Munich Pettenkoferstr. 8a, D-8000 Munich 2, Germany

Abstract

A 21–year-old woman suffering from bipolar affective disorder developed systemic lupus erythematosus (SLE) with characteristic laboratory findings, 18 months after starting carbamazepine maintenance treatment. SLE receded after withdrawal of carbamazepine and treatment with anti-inflammatory drugs. Although both the spontaneous occurrence of SLE and the psychosis as a sign of CNS involvement of SLE cannot be excluded, SLE could be considered as an adverse effect of carbamazepine.

Type
Brief Reports
Copyright
Copyright © 1992 The Royal College of Psychiatrists 

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