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Combination Treatment with Noradrenalin and Serotonin Reuptake Inhibitors in Resistant Depression

Published online by Cambridge University Press:  02 January 2018

R. Seth ,
A. L. Jennings ,
J. Bindman ,
J. Phillips  and
K. Bergmann
R. Seth*
Affiliation:
The Maudsley Hospital, Denmark Hill, London SE5 8AZ
K. Bergmann
Affiliation:
Bethlem Royal and Maudsley Hospitals
*
∗Correspondence
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Abstract

Eight cases of resistant recurrent depression were treated with a combination of nortriptyline and a new serotonin reuptake inhbitor, with or without concurrent lithium therapy. Significant improvement was seen in all patients where other drug regimes and ECT had been ineffective. No adverse reactions occurred in any of our patients, seven of whom were elderly. The combination treatment was more effective than individual therapies alone.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 161 , Issue 4 , October 1992 , pp. 562 - 565
Copyright
Copyright © 1992 The Royal College of Psychiatrists 

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