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A Pilot Study of Schizophrenia-Like Psychosis in Epilepsy Using Single-Photon Emission Computerised Tomography

Published online by Cambridge University Press:  02 January 2018

E. Jane Marshall*
Affiliation:
Sections of Genetics and Neuropsychiatry, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, and Epilepsy Unit and Neuropsychiatry, Maudsley Hospital, Denmark Hill, London SE5 8AZ
G. M. S. Syed
Affiliation:
Department of Nuclear Medicine, King's College Hospital, Denmark Hill, London SE5
P. B. C. Fenwick
Affiliation:
Institute of Psychiatry, De Crespigny Park, London SE5 8AF, and Maudsley Hospital, Denmark Hill, London SE5 8AZ
W. A. Lishman
Affiliation:
Institute of Psychiatry, De Crespigny Park, London SE5 8AF, and Maudsley Hospital, Denmark Hill, London SE5 8AZ
*
Correspondence

Abstract

In a pilot study, SPECT was used to explore differences in rCBF between a group of patients with schizophrenia-like psychoses of epilepsy (SLPE) and a matched group of epileptic controls. Five patients in each group were investigated and those with SLPE showed significant reductions in the index of rCBF in the left medial temporal region. These differences are being investigated further.

Type
Research Article
Copyright
Copyright © The Royal College of Psychiatrists 

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