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Antidepressant Effect of Lithium in Patients with Systemic Lupus Erythematosus and Cerebral Infarction, Treated with Corticosteroid

Published online by Cambridge University Press:  02 January 2018

Taro Ohji
Affiliation:
Second Department of Internal Medicine
Kazuhiko Abe
Affiliation:
University of Occupational and Environmental Health, Kitakyushu, Japan

Abstract

Two depressive patients with systemic lupus erythematosus (SLE) and cerebral infarction, while being treated with corticosteroid, are described. In both cases, lithium was remarkably effective and no severe side-effects occurred. These findings suggest that lithium can be a useful antidepressant agent in the treatment of depressive SLE patients.

Type
Brief Reports
Copyright
Copyright © The Royal College of Psychiatrists 

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References

Blier, P. & de Montigny, C. (1985) Short-term lithium administration enhances serotonergic neurotransmission: electrophysiological evidence in the rat CNS. European Journal of Pharmacology, 113, 6977.CrossRefGoogle ScholarPubMed
Dickinson, S. L., Kennett, G. A. & Curzon, G. (1985) Reduced 5-hydroxytryptamine-dependent behaviour in rats following chronic corticosterone treatment. Brain Research, 345, 1018.CrossRefGoogle Scholar
Falk, W. E., Mahnke, M. W. & Poskanzer, D.C. (1979) Lithium prophylaxis of corticotropin-induced psychosis. Journal of the American Medical Association, 241, 10111012.CrossRefGoogle ScholarPubMed
Hall, R. C. W., Popkin, M. K., Stickney, S. K., et al (1979) Presentation of the steroid psychoses. Journal of Nervous and Mental Disease, 167, 229236.Google Scholar
Heine, B. E. (1969) Psychiatric aspects of systemic lupus erythematosus. Acta Psychiatrica Scandinavica, 45, 307326.CrossRefGoogle ScholarPubMed
Robinson, R. G. & Price, T. R. (1982) Post-stroke depressive disorders: a follow-up study of 103 patients. Stroke, 13, 635641.Google Scholar
Siegal, F. P. (1978) Lithium for steroid-induced psychosis. New England Journal of Medicine, 299, 155156.Google Scholar
Terao, T., Yanagihara, N., Abe, K., et al (1992) Lithium chloride stimulates catecholamine synthesis and secretion in cultured bovine adrenal medurally cells. Biological Psychiatry, 31, 10381049.CrossRefGoogle Scholar
Worrall, E. P. (1986) Lithium augmentation of tricyclics. British Journal of Psychiatry, 149, 520521.CrossRefGoogle ScholarPubMed
Worrall, E. P. Moody, J. P., Peet, M., et al (1979) Controlled studies of the acute antidepressant effects of lithium. British Journal of Psychiatry, 135, 255262.Google Scholar
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