Hostname: page-component-8448b6f56d-qsmjn Total loading time: 0 Render date: 2024-04-19T19:44:02.330Z Has data issue: false hasContentIssue false

Objective Evaluation of Pain Perception in Patients with Schizophrenia

Published online by Cambridge University Press:  02 January 2018

R. Guieu*
Affiliation:
Laborataire de Biochimie, Faculté de Médecine Secteur Nord, Bd P. Dramard, 13015 Marseille, France
J. C. Samuélian
Affiliation:
Chef de Service, Psychiatrie des Hospitaux
H. Coulouvrat
Affiliation:
Interne en Psychiatrie, Service de Psychiatrie d'Adultes, CHU Timone, Marseille, France
*
Correspondence

Abstract

The pain thresholds of patients with schizophrenia often seem to differ from those of healthy subjects. In the present study we assessed the pain thresholds of ten patients with schizophrenia, and of ten controls, by measuring the leg flexion nociceptive reflex threshold: the stimulation threshold at which this reflex is triggered, is known to be correlated with the pain threshold. Our conclusion is that, in most cases, the increase in pain threshold is the result of ‘attitude’ and not of alterations in brain function.

Type
Short Papers
Copyright
Copyright © 1994 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Brambilla, F., Facchinetti, F., Petraglia, F., et al (1984) Secretion pattern of endogenous opioids in chronic schizophrenia. American Journal of Psychiatry, 141, 11831188.Google Scholar
Clement-Jones, V., McLoughlin, L., Tomlin, S., et al (1980) Increased beta-endorphin but not met-enkephalin levels in human cerebrospinal fluid after acupuncture for recurrent pain. Lancet, ii, 946950.10.1016/S0140-6736(80)92106-6CrossRefGoogle Scholar
Fishbain, D. (1982) Pain insensitivity in psychosis. Annals of Emergency Medicine, 11, 630632.10.1016/S0196-0644(82)80210-2CrossRefGoogle ScholarPubMed
Geschwind, N. (1977) Insensitivity to pain in psychotic patients. New England Journal of Medicine, 296, 1480.Google Scholar
Gillman, M. A. & Lichtigfeld, F. J. (1985) A pharmacological overview of opioid mechanisms mediating analgesia and hyperalgesia. Neurological Research, 7, 105119.10.1080/01616412.1985.11739709Google Scholar
Guieu, R., Blin, O., Pouget, J., et al (1992) High level sportsmen and nociceptive flexion reflex of the lower limb. Canadian Journal of Neurological Sciences, 19, 6971.CrossRefGoogle Scholar
Lewis, C. (1937) Diagnostic problems of acute surgical conditions of the abdomen in psychotic patients. Medicine Bulletin of the Veteran Administration, 13, 314320.Google Scholar
Pickar, D., Vartanian, F., Bunney, W. E., et al (1982) Short-term naloxone administration in schizophrenic and manic patients: A World Health Organization collaborative study. Archives of General Psychiatry, 39, 313319.10.1001/archpsyc.1982.04290030047009Google Scholar
Rosenthal, S. H., Porter, K. A. & Coffey, B. (1990) Pain insensitivity in schizophrenia, case report and review of the literature. General Hospital Psychiatry, 12, 319322.10.1016/0163-8343(90)90050-MGoogle Scholar
Willer, J. C., Boureau, F. & Albe-Fessard, D. (1979) Supraspinal influences on nociceptive flexion reflex and pain sensation in man. Brain Research, 179, 6168.Google ScholarPubMed
Submit a response

eLetters

No eLetters have been published for this article.