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Neuroleptic Medication for Dystonia

Reciprocal Relationship Between Effects on Motor Function and Mood

Published online by Cambridge University Press:  02 January 2018

C. S. Young ,
J. B. Stewart  and
G. W. Fenton
C. S. Young
Affiliation:
Royal Dundee Liff Hospital, Dundee
J. B. Stewart*
Affiliation:
Royal Dundee Liff Hospital, Dundee
G. W. Fenton
Affiliation:
Ninewells Hospital and Medical School, Dundee
*
Dr Stewart, Department of Psychiatry, Royal Dundee Liff Hospital, Dundee DD2 5NF
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Abstract

Background

The presence of dysphoric symptoms associated with neuroleptic medication is commonly reported.

Method

Neuroleptic treatment of a segmental dystonia resulted in a disabling depressive illness, which when treated with antidepressants led to the return of the involuntary movements.

Results

The use of several different antidepressants and neuroleptics confirmed the association between drugs and symptoms. Genetic studies excluded “poor metaboliser status” as a reason for the patient's sensitivity to these drugs.

Conclusions

The case illustrates a delicate imbalance between dose of neuroleptic medication and depressive symptoms. We should be aware of the possibility of mood changes in patients treated with neuroleptics for a variety of conditions.

Type
Short Papers
Information
The British Journal of Psychiatry , Volume 165 , Issue 3 , September 1994 , pp. 384 - 386
Copyright
Copyright © Royal College of Psychiatrists, 1994 

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