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A Self-Rating Scale for Measuring Neuroleptic Side-Effects

Validation in a Group of Schizophrenic Patients

Published online by Cambridge University Press:  02 January 2018

Jennifer C. Day
Affiliation:
Department of Clinical Psychology, University of Liverpool, Liverpool
Graham Wood
Affiliation:
Department of Clinical Psychology, University of Liverpool, Liverpool
Mike Dewey
Affiliation:
Royal Preston Hospital, Preston
Richard P. Bentall*
Affiliation:
Academic Department of Psychiatry, Royal Liverpool University Hospital, Liverpool
*
Professor Bentall, Department of Clinical Psychology, Whelan Building, University of Liverpool, PO Box 147, Liverpool L69 3BX

Abstract

Background

A study was conducted to validate a comprehensive self-rating scale for measuring side-effects of neuroleptic drugs.

Method

The Liverpool University Neuroleptic Side Effect Rating Scale (LUNSERS), which includes ‘red herring’ items, was twice administered to 50 DSM–III–R schizophrenic patients, who were also interviewed using the UKU side-effect rating scale; 50 unmedicated controls also completed the LUNSERS.

Results

The test-retest reliability of the LUNSERS was good (r = 0.811, P< 0.001) as was its concurrent validity against the UKU (r = 0.828, P< 0.001). Scores correlated with chlorpromazine equivalent doses (r = 0.310, P< 0.02). ROC analysis demonstrated that the scale discriminated between patients and non-medicated controls, who scored differently for real side-effects but not for ‘red herring’ items.

Conclusions

The LUNSERS is an efficient, reliable and valid method of assessing neuroleptic side-effects.

Type
Papers
Copyright
Copyright © Royal College of Psychiatrists, 1995 

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