Hostname: page-component-8448b6f56d-c4f8m Total loading time: 0 Render date: 2024-04-17T05:51:43.216Z Has data issue: false hasContentIssue false

Type of hospital setting and treatment outcome with heroin addicts

Results from a randomised trial

Published online by Cambridge University Press:  03 January 2018

John Strang*
Affiliation:
National Addiction Centre, Institute of Psychiatry/The Maudsley
Isaac Marks
Affiliation:
Department of Psychiatry, Institute of Psychiatry/The Maudsley
Sharon Dawe
Affiliation:
Department of Psychology, Institute of Psychiatry
Jane Powell
Affiliation:
Department of Psychology, Institute of Psychiatry and Drug Unit, National Addiction Centre
Michael Gossop
Affiliation:
National Addiction Centre, Institute of Psychiatry/The Maudsley
David Richards
Affiliation:
Department of Psychology, Institute of Psychiatry
Jeffrey Gray
Affiliation:
Department of Psychology, Institute of Psychiatry
*
Professor John Strang, Addiction Sciences Building, 4 Windsor Walk, Denmark Hill, London SE5 8AF

Abstract

Background

General psychiatrists have recently been encouraged to provide treatment to heroin addicts, including in-patient detoxification. No comparison has previously been made of specialist versus general psychiatric in-patient care.

Method

During a randomised study of cue exposure, 186 opiate addicts were also randomised to either specialist in-patient (DDU; n=115) or general psychiatric (GEN; n=71) wards in the same hospital.

Results

From pre-treatment (post-randomisation) onwards, patient outcomes differed across the two in-patient settings. Of the original randomised sample, significantly more DDU than GEN subjects accepted their randomisation (100 v. 77%), were subsequently admitted (60 v. 42%), and completed in-patient detoxification (45 v. 18%). Of patients admitted, more DDU than GEN patients completed detoxification (75 v. 43%). During seven-month follow-up, of those 43 patients who reached the end of treatment, significantly more ex-DDU than ex-GEN subjects were opiate-free.

Conclusions

From pre-treatment onwards, significant differences in process and outcome were found after allocation to treatment on either DDU or GEN. Further randomised studies are required to replicate and explain these findings.

Type
Papers
Copyright
Copyright © 1997 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Advisory Council on the Misuse of Drugs (1982) Treatment and Rehabilitation Report. London: HMSO.Google Scholar
Advisory Council on the Misuse of Drugs (1993) AIDS and Drug Misuse: Update. London: HMSO.Google Scholar
Beam, J., Gossop, M. & Streng, J. (1996) A randomised double-blind comparison of lofexidine and methadone in the inpatient treatment of opiate withdrawal. Drug and Alcohol Dependence, 43, 8791.Google Scholar
Black, D. (1988) Drug misuse: policy and service development. Journal of the Royal Society of Health, 108, 8389.CrossRefGoogle ScholarPubMed
British Medical Association (1997) The Misuse of Drugs. Amsterdam: Harwood Academic.Google Scholar
Dawe, S., Powell, J., Richards, D., et al (1993) Does postwithdrawal cue exposure improve outcome in opiate addiction? A controlled trial. Addiction, 88, 12331245.CrossRefGoogle ScholarPubMed
De Aranjo, L. A., Ito, L., Marks, I. M., et al (1995) Does imagined exposure to the consequences of not ritualising enhance live exposure for OCD? A controlled trial: I. Main outcome. British Journal of Psychiatry, 167, 6570.Google Scholar
Edwards, D. R. & Guthrie, S. (1967) A controlled trial of in-patient and out-patient treatment of alcohol dependence. Lancet, i, 555559.Google Scholar
Finney, J., Hahn, A. & Moos, R. (1996) The effectiveness of inpatient and outpatient treatment for alcohol abuse: the need to focus on mediators and moderators of setting effects. Addiction, 91, 17731796.CrossRefGoogle ScholarPubMed
Gerstein, D. R. & Harwood, H. J. (eds) (1990) Treating drug problems. In Volume I – Study of the Evolution, Effectiveness and Financing of Public and Private Drug Treatment Systems. Washington: National Academy Press.Google Scholar
Ghodse, A. H., London, M., Bewley, T. H., et al (1987) In-patient treatment for drug abuse. British Journal of Psychiatry 151, 7275.Google Scholar
Gossop, M., Green, L., Phillips, G., et al (1987) What happens to opiate addicts immediately after treatment?: a prospective follow-up study. British Medical Journal, 294, 13771380.CrossRefGoogle ScholarPubMed
Howard, K., Cox, M. & Saunders, S. (1990) Attrition in substance abuse comparative treatment research: the illusion of randomisation. In Psychotherapy and Counselling in the Treatment of Drug Abuse (NIDA Research Monograph no. 104) (eds Onken, L. S. & Blaine, J.), pp. 6679. Rockville. MD: National Institute on Drug Abuse.Google Scholar
Kasvikis, Y., Bradley, B., Gossop, M., et al (1990) Clonidine versus long- and short-term methadone-aided withdrawal from opiates: an uncontrolled comparison. International Journal of the Addictions, 25, 11691178.Google Scholar
Mattick, R. & Hall, W. (1996) Are detoxification programmes effective? Lancet, 347, 97100.Google Scholar
McLellan, A. T., Luborsky, L., O'Brien, C. P., et al (1980) An improved diagnostic evaluation instrument for substance abuse patients: the Addiction Severity Index (ASI). Journal of Nervous and Mental Diseases, 168, 2633.CrossRefGoogle Scholar
Oppenheimer, E., Sheehan, M. & Taylor, C. (1990) What happens to drug misusers?: a medium term follow up of subjects new to treatment. British Journal of Addiction, 85, 12551260.Google Scholar
Orford, J. & Edwards, G. (1977) Alcoholism: A Study of Treatment and Advice, with a Study of the Influence of Marriage (Maudsley Monograph no. 26). Oxford: Oxford University Press.Google Scholar
Powell, J., Dawe, S., Richards, D., et al (1993) Can opiate addicts tell us about their relapse risk? Subjective predictors of clinical prognosis. Addictive Behaviors, 18, 473490.Google Scholar
Strang, J. & Gossop, M. (1990) Comparison of linear versus inverse exponential methadone reduction curves in the detoxification of opiate addicts. Addictive Behaviours, 15, 541547.Google Scholar
Tantam, D., Donmall, M., Webster, A., et al (1993) Can general practitioners and general psychiatrists be expected to look after drug misusers? Results from evaluation of a non-specialist treatment policy. British Journal of General Practice, 43, 470474.Google Scholar
Thornicroft, G., Colson, L. & Marks, I. (1991) An in-patient behavioural psychotherapy unit: Description and audit. British Journal of Psychiatry, 158, 362367.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.