Hostname: page-component-8448b6f56d-c4f8m Total loading time: 0 Render date: 2024-04-18T17:39:55.878Z Has data issue: false hasContentIssue false

Outcome of anxiety and depressive disorders in primary care

Published online by Cambridge University Press:  03 January 2018

Clare Ronalds
Affiliation:
University Department of General Practice, Rusholme Health Centre
Francis Creed*
Affiliation:
University Department of Psychiatry, Manchester Royal Infirmary
Kit Stone
Affiliation:
University Department of Psychiatry, Manchester Royal Infirmary
Sarah Webb
Affiliation:
University Department of General Practice, Rusholme Health Centre
Barbara Tomenson
Affiliation:
University Department of Psychiatry, Manchester Royal Infirmary
*
Professor Francis Creed, Department of Psychiatry, Rawnsley Building, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL

Abstract

Background

Factors related to the outcome of depression and anxiety in primary care are not fully understood.

Method

Adult patients in general practice with depressive, anxiety or panic disorder (n=148; DSM–III–R criteria) were studied prospectively for six months to determine the factors most closely associated with outcome. The Psychiatric Assessment Schedule, Hamilton Depression Rating Scale, Clinical Anxiety Scale and Life Events and Difficulties Schedule interviews were performed at index consultations and repeated six months later. Variables associated with outcome were assessed by multiple regression analysis.

Results

Good outcome was predicted by mild depression at initial assessment, high educational level, and being in employment. At follow-up the most important predictor of improvement was reduction in marked difficulties over the six months. Recognition and management by the GP was most frequent in patients with severe disorder; such patients were least likely to improve because of the severity of their depression and marked social difficulties.

Conclusions

This naturalistic study helps to provide a framework for further studies with more precisely defined groups of people with depression. An effective treatment strategy for people with marked depression and ongoing social difficulties is especially needed.

Type
Papers
Copyright
Copyright © 1997 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders (3rd edn, revised) (DSM–III–R) Washington, DC: APA.Google Scholar
Barrett, J. E., Barrett, J. A., Oxman, T. E., et al (1988) The prevalence of psychiatric disorders in a primary care practice. Archives of General Psychiatry, 45, 11001106.CrossRefGoogle Scholar
Blacker, C. V. R. & Clare, A. W. (1987) Depressive disorder in primary care. British Journal of Psychiatry, 150, 737751.CrossRefGoogle ScholarPubMed
Brown, C. & Schulberg, H. C. (1995) The efficacy of psychosocial treatments in primary care: A review of randomized clinical trials. General Hospital Psychiatry, 17, 414424.CrossRefGoogle ScholarPubMed
Brown, G. W. & Harris, T. (1978) Social Origins of Depression. London: Tavistock Publications.Google ScholarPubMed
Brown, G. W., Adler, Z. & Bifulco, A. (1988) Life events, difficulties and recovery from chronic depression. British Journal of Psychiatry, 152, 487498.CrossRefGoogle ScholarPubMed
Corney, R. H. (1981) Social work effectiveness in the management of depressed women – a clinical trial. Psychological Medicine, 11, 417423.CrossRefGoogle ScholarPubMed
Coyne, J. C., Schwenk, T. L. & Fechner-Bates, S. (1995) Nondetection of depression by primary care physicians reconsidered. General Hospital Psychiatry, 17, 312.CrossRefGoogle ScholarPubMed
Coryell, W., Akiska, H., Leon, A., et al (1994) The time course of nonchronic major depressive disorder. Uniformity across episodes and sample. Archives of General Psychiatry, 51, 405410.CrossRefGoogle Scholar
Creed, F. & Marks, B. (1989) Liaison psychiatry in general practice: a comparison of the liaison attachment scheme and shifted outpatient clinic models. Journal of Royal College of General Practitioners, 39, 514517.Google ScholarPubMed
Dean, C., Surtees, P. G. & Sashidaran, S. P. (1983) Comparison of research diagnostic systems in an Edinburgh community sample. British Journal of Psychiatry, 142, 247256.CrossRefGoogle Scholar
Dowrick, C. & Buchan, I. (1995) Twelve month outcome of depression in general practice: does detection or disclosure make a difference? British Medical Journal, 311, 12741276.CrossRefGoogle ScholarPubMed
George, L. K., Blazer, D. G., Hughes, D. C., et al (1989) Social support and the outcome of major depression. British Journal of Psychiatry, 154, 478485.CrossRefGoogle ScholarPubMed
Goldberg, D. P. (1978) Manual of the General Health Questionnaire. Windsor: NFER–Nelson.Google Scholar
Goldberg, D. P. & Blackwell, B. (1970) Psychiatric illness in general practice. British Medical Journal, 2, 439443.CrossRefGoogle Scholar
Hamilton, M. (1967) Development of a rating scale for primary depressive illness. British Journal of Social and Clinical Psychology, 6, 278296.CrossRefGoogle ScholarPubMed
Karlsson, H., Lehtinen, V. & Joukamaa, M. (1995) Psychiatric morbidity among frequent attender patients in primary care. General Hospital Psychiatry, 17, 1925.CrossRefGoogle ScholarPubMed
Katon, W. (1995) Will improving detection of depression in primary care lead to improved depressive outcomes. General Hospital Psychiatry, 17, 12.CrossRefGoogle ScholarPubMed
Katon, W. & Schulberg, H. (1992) Epidemiology of depression in primary care. General Hospital Psychiatry, 14, 137147.CrossRefGoogle ScholarPubMed
Kedward, H. (1969) The outcome of neurotic illness in the community. Social Psychiatry, 4, 104.CrossRefGoogle Scholar
Kessler, L. G., Cleary, P. D. & Burke, J. D. (1985) Psychiatric disorders in primary care. Archives of General Psychiatry, 42, 583587.CrossRefGoogle ScholarPubMed
Mann, A., Jenkins, R. & Belsey, E. (1981) The twelve month outcome of patients with neurotic illness in general practice. Psychological Medicine, 2, 535550.CrossRefGoogle Scholar
Ormel, J., Van den Brink, W., Koeter, M. W. J., et al (1990) Recognition, management and outcome of psychological disorders in primary care: a naturalistic follow-up study. Psychological Medicine, 20, 909923.CrossRefGoogle ScholarPubMed
Ormel, J., Oldehinkel, T., Brilman, E., et al (1993) Outcome of depression and anxiety in primary care. A three-wave 3½ - year study of psychopathology and disability. Archives of General Psychiatry, 50, 759766.CrossRefGoogle ScholarPubMed
Ormel, J., & Tiermens, B. (1995) Recognition and treatment of mental illness in primary care: Towards a better understanding of a multifaceted problem. General Hospital Psychiatry, 17, 160164.CrossRefGoogle ScholarPubMed
Parker, G., Holmes, S. & Manicavasagar, V. (1986) Depression in general practice: caseness, natural history and predictors of outcome. Journal of Affective Disorders, 10, 2735.CrossRefGoogle ScholarPubMed
Paykel, E., Hollyman, J., Freeling, P., et al (1988) Predictors of therapeutic benefit of amitriptyline in mild depression: a general practice placebo-controlled trial. Journal of Affective Disorders, 14, 8395.CrossRefGoogle ScholarPubMed
Piccinelli, M. & Wilkinson, G. (1994) Outcome of depression in psychiatric settings. British Journal of Psychiatry, 164, 297304.CrossRefGoogle ScholarPubMed
Sargeant, J. K., Bruce, M. L., Florio, L. P., et al (1990) Factors associated with 1-year outcome of major depression in the community. Archives of General Psychiatry, 47, 519526.CrossRefGoogle ScholarPubMed
Sartorius, N., Bedirhan, U., Costa e Silva, J.-A., et al (1993) An international study of psychological problems in primary care. Archives of General Psychiatry, 50, 819824.CrossRefGoogle Scholar
Scott, A. I. F. & Freeman, C. P. L. (1992) Edinburgh primary care depression study: treatment outcome, patient satisfaction, and cost after 16 weeks. British Medical Journal, 304, 883887.CrossRefGoogle Scholar
Simon, G., Ormel, J., Von Korff, M., et al (1995) Health care costs associated with depressive and anxiety disorders in primary care. American Journal of Psychiatry, 152, 352357.Google ScholarPubMed
Snaith, R. P., Baugh, S. J., Clayden, A. D., et al (1982) The Clinical Anxiety Scale: a modification of the Hamilton Anxiety Scale. British Journal of Psychiatry, 141, 518523.CrossRefGoogle Scholar
Surtees, P. G. & Ingham, J. G. (1980) Life stress and depressive outcome: application of a dissipation model to life events. Social Psychiatry, 15, 2131.CrossRefGoogle Scholar
Tyrer, P., Casey, P. R., Seivewright, H., et al (1988) A survey of the treatment of anxiety disorders in general practice. Postgraduate Medical Journal, 64, 2731.Google ScholarPubMed
Von Korff, N., Shapire, S., Burke, J. D., et al (1987) Anxiety and depression in a primary care clinic. Archives of General Psychiatry, 44, 152156.CrossRefGoogle Scholar
Whitehouse, C. R. (1987) A survey of the management of psychosocial illness in general practice in Manchester. Journal of Royal College of General Practitioners, 37, 112115.Google ScholarPubMed
Submit a response

eLetters

No eLetters have been published for this article.