The following case presents certain points of interest. The extreme prominence of pain crises in the beginning is unusual. Suicidal tendencies in general paralysis are sufficiently uncommon to be noteworthy, though they are by no means as uncommon as is generally supposed. The same may be said of delusions of conjugal infidelity. Finally, multiple lipomata occurring in this disease have not, as far as I am aware, attracted the notice of any English author.