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On the Wassermann Reaction in 172 Cases of Mental Disorder (Cardiff City Mental Hospital) and 66 Control Cases, Syphilitic and other (chiefly from Cardiff Infirmary), with Historical Survey for the Years 1906–10, inclusive: Comments and Conclusions.(1)

Published online by Cambridge University Press:  19 February 2018

H. A. Scholberg
Affiliation:
Cardiff Infirmary and the City Mental Hospital
Edwin Goodall
Affiliation:
Cardiff City Mental Hospital

Extract

The sero-diagnosis of a syphilitic infection, commonly known as the “Wassermann reaction,” is based on the work published by Bordet in 1899, and Bordet and Gengou in 1901. It was there shown that the absence of hæmolysis could be made available as a naked-eye test indicative of a specific infection, and that the occurrence of hæmolysis negatived the existence of such infection. This reaction they showed was due to the fact that the anti-bodies produced by an infection were able to fix complement in the presence of the corresponding antigen, so that an attempt to complete an hæmolytic system after complement had been absorbed was ineffectual, and the homologous red blood-corpuscle remained intact, though exposed to the action of an inactivated homologous hæmolytic serum.

Type
Part I.—Original Articles
Copyright
Copyright © Royal College of Psychiatrists, 1911 

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References

Maslakowetz, u. Liebermann, . —“Theorie etc. d. Reaktion v. Wassermann,” Centralbl. f. Bakteriol., Bd. xlvii, Heft 3.Google Scholar
Marie, et Levaditi, . —“Séro-Réaction de la Syphilis dans la Paralysie Générale,” Annales Med-Psych., année lxvie, No. 1, Juillet Aôut, 1908.Google Scholar
Marie, et Levaditi, . —“Les ‘Anticorps Syphilitiques’ dans le liquide céphalo-rachidien des paralytiques généraux et des tabetiques,” Annales de l'Inst. Pasteur, t. 21, 1907.Google Scholar
Foerster-Bonn, R.“Uber das Wassermann-Plautsche Verfahren der Sero-diagnostik bei syphilidogenen Erkrankungen des Zentralnervensystems,” Allg. Zeit. f. Psych., Bd. lxv, Heft 1 (abstract).Google Scholar
Plaut, . —“Uber den jetzigen Stand der serologischen Untersuchung bei den syphilidigenen Psychosen,” Allg. Zeit. f. Psych., Bd. lxiv, Heft 4, 1907.Google Scholar
Plaut, . —“Die Lues Paralyse-Frage.” Allg. Zeit. f. Psych., Bd. lxvi, Heft 2.Google Scholar
Plaut, . —Die Wassermannsche Serodiagnostik der Syphilis in ihrer Anwendung auf die Psychiatrie. (Gustav Fischer, Jena, 1909.) (Particularly valuable memoir—extensive bibliography.) Google Scholar
Stertz, . —“Die Serodiagnostik in der Psychiatrie und Neurologie,” Allg. Zeit. f. Psych., Bd. lxv, Heft 4.Google Scholar
Jarkowski, J., et Raichman, L.“Quelques Rémarques sur la Reaction de Wassermann dans le Tabes et la Paralysie Générale,” Comptes Rendus de la Société de Biologie, t. 66, 1909.Google Scholar
Morgenroth, and Stertz, . —“Uber den Nachweis syphilitischer Antikörper im Liquor cerebrospinalis von Paralytikern nach dem Wassermann-Plautschen Verfahren der Komplementablenkung,” Archiv f. Path. Anat. u. Phys., 18 Folge 188, 1907.Google Scholar
Levaditi, , Ravaut, , et Yamanouchi, . —“Localisation Nerveuse de la Syphilis et Propriétés du Liquide Céphalo-Rachidien,” Comptes Rendus, Soc. de Biol., 64, 1908.Google Scholar
Marinesco, G.“Sur le Diagnostic de la Paralysie Générale et du Tabes par les Nouvelles Methodes,” Comptes Rendus, Soc. de Biol., 66, 1909.Google Scholar
Kaffka, Victor. —“Ueber die Klinische Bedeutung der Complementbindungsreaktion im Liquor cerebrospinalis, speziell bei der progressiven Paralyse,” Monatsschr. f. Psych. u. Neurol., 24, 1908.CrossRefGoogle Scholar
Marie, A. (de Villejuif), Levaditi, C., et Yamanouchi, T.“La Réaction de Wassermann dans la Paralysie Générale,” Comptes Rendus et Mem. de la Soc. de Biol. (Séance du 1-er Février), 64, 1908.Google Scholar
Levaditi, C., et Yamanouchi.—“La Séro-Réaction de la Syph. et de la Par. Gen.,” Comptes Rendus et Mem. de la Soc. de Biol. (Séance du 29 Fév.) Google Scholar
Raviart, G., Breton, M., et Petit, G.“Réchérches sur la Reaction de Wassermann chez quatre cents Aliénes,” Comptes Rendus et Mem. de la Soc. de Biol. (Séance du 29 Fév) Google Scholar
Smith, Henderson, and Candler, J. P.“On the Wassermann Reaction in General Paralysis of the Insane,” Brit Med. Journ., July 24th, 1909.Google Scholar
Boas, and Neve, . —“Die Wassermannsche Reaktion bei Dementia Paralytica,” Berlin. klin. Woch., No. 29, July, 1910.Google Scholar
Lesser, Fritz. —“Tubes und Paralyse im Lichte der neuren Syphilis forschung,” Berlin. klin. Woch., 45, ii, No. 39, 1908.Google Scholar
Rossi, G.“Dati statistici e considerazioni critiche sulla prova di Wassermann nella diagnosi della sifilide, della tabe e della paralisi progressiva,” Revista di Patologia Nervosa e Mentale, anno. xiv, fasc. 1. (Extensive bibliography.) Google Scholar
Jones, Ernest. —“A Review of our Present Knowledge concerning the Sero-Diagnosis of General Paralysis,” Amer. Journ. Insan., lxv, April, 1909. (Full bibliography.) Google Scholar
Eichelberg, u. Pförtner, . —“Die Praktische Verwertbarkeit der verschiedenen Untersuchungensmethoden des Liquor cerebrospinalis für die Diagnostik der Geistes und Nervenkrankheiten,” Monats. f. Psych. u. Neurol., Vol. xxv, 1909.Google Scholar
Obregia, and Bruckner, . —“Le Liquide Céphalo-Rachidien dans la Paralysie Générale Stationnaire, soumis à la Réaction de Wassermann,” Comptes Rendus Soc. de Biol., 66, 1909. (Séance du 16 Dec.) Google Scholar
Eichelberg-Göttingen, . —Allg. Zeit. f. Psych., Bd. lxvi, Heft 3 and 4.Google Scholar
Edel, Max. —“Die Wassermann Reaction bei der progressiven Paralyse und Paralyseähnlichen Erkrankung,” Allg. Zeit. f. Psych., Bd. lxvi, Heft 1.Google Scholar
Bruckner, . —“Norddeutscher Verein für Psychiatrie und Neurol.,” Allg. Zeit. f. Psych., Bd. lxvi, Heft 6 (abstract).Google Scholar
Kleineberger, Ludwig. —“Uber die Juvenile Paralyse.,” Allg. Zeit. f. Psych., Bd. lxv, Heft 6.Google Scholar
Mackintosh, . —Lancet, May, 1909, p. 1520.Google Scholar
Rossi, O.Estratto dai Lavori e Reviste de Chimica e Microscopia Clinica, Vol. i, fasc. 6, February, 1909. (Extensive bibliography.)Google Scholar
Billstrωm, J.“Lumbal punktionens diagnostika betydelse särskild vid börjande Paralysie Générale,” Hygiea, No. 3, March, 1909.Google Scholar
Scott-Williamson, .—“The Cerebro-spinal Fluid in General Paralysis and the Nervous Lues,” Journ. of Ment. Sci., October, 1909.Google Scholar
Ensor, . —“Syphilis in Insanity as Determined by the Wassermann Reaction,” Rev. of Neurol. and Psych., Vol. viii, No. 10, October, 1910 (abstract).Google Scholar
Dean, . —“An Examination of the Blood-Serum of Idiots by the Wassermann Reaction,” Lancet, July 23rd, 1910.Google Scholar
Apelt, . —“Zum Werte der Phase 1 (Globulin-Reaktion) usw,” Archiv f. Psych., Bd. xlvi, 1910.Google Scholar
Wassermeyer, and Bering, . —“Die Wassermann-Reaktion in der Psychiatrie und Neurologie mit besonderer Berücksichtigung der Paralyse, Tabes u. Lues cerebri, bzw. cerebrospinalis,” Archiv f. Psych., Bd. xlvii, Heft 2.Google Scholar
Wassermeyer, . —“Verhandlungen Psychiatrischer Vereine,” Allg. Zeit. f. Psych., Bd. lxvii, Heft 5.Google Scholar
Hubner, . —Allg. Zeit. f. Psych., Bd. lxvi, Heft 3 and 4.Google Scholar
Zaloziecki, (quoted by Matusch)—Allg. Zeit. f. Psych., Bd. lxvii, Literaturheft.Google Scholar
Szecsis, (quoted by Matusch).—Allg. Zeit. f. Psych., Bd. lxvii, Literaturheft.Google Scholar
Morton, . —Journ. of Ment. Sci., January, 1911.Google Scholar
Baccelli, . —Riv. Sperim., Vol. xxxvi, fasc. 4, 1910.Google Scholar
Fröderström, and Wigert, . —Monats. f. Psych. u. Neurol., Bd. xxviii, 1910.Google Scholar
Nonne, and Holzmann, . —Monats. f. Psych. u. Neurol., Bd. xxvii, 1910.Google Scholar
Hallager, . —Monats. f. Psych. u. Neurol., Bd. xxviii, 1910.Google Scholar
Marie, . —Rev. de Psych., No. 10, p. 567.Google Scholar
Muirhead, W.“The Wassermann Reaction in Blood and Cerebrospinal Fluid,” Journ. Ment. Sci., October, 1910.Google Scholar
Assmann, . —Rev. of Neurol. and Psych., February, 1911 (Zeit. f. Nerven., Bd. xl, Heft 1 and 2, 1910).Google Scholar
Noguchi, (quoted by Bayly, ).—Quart. Journ. Med., January, 1911.Google Scholar
Mott, , Candler, and Henderson, . —Quart. Journ. Med.Google Scholar
Bayly, . —Quart. Journ. Med., Vol. iv, p. 232.Google Scholar
Meltzer, S. J.—Quoted in Rev. of Neurol. and Psych., January, 1911.Google Scholar
Flashman, Fronde, and Graham, Butler. —“The Method of Diagnosis by means of Complement-Fixation, as applied to Syphilis and General Paralysis: The Wassermann Reaction,” Report of the Pathological Laboratory of the Lunacy Department, New South Wales Government, Vol. ii, Part I, 1910, p. 25.Google Scholar
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