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The Colloidal Gold Reaction with Cerebrospinal Fluid

Published online by Cambridge University Press:  19 February 2018

Thomas Houston
Affiliation:
Laboratory of the Royal Victoria Hospital, Belfast
Edward Armstrong
Affiliation:
Laboratory of the Royal Victoria Hospital, Belfast

Extract

The history of the colloidal gold reaction is one of great interest. In 1901 Zsigmondy used the precipitation of colloidal gold by proteins as a means of determining quantitatively their amount in given solutions. He discovered that solutions of protein give protection to colloidal solutions of gold up to a certain point, and he determined the so-called goldzahl for various protein substances, by which is meant the number of milligrammes of protein employed, just sufficient to prevent the precipitation of 10 c.c. of colloidal gold of a percentage of .0053 in the presence of 1 c.c. of 10 per cent. sodium chloride. By this method it can be determined whether a given protein is absolutely pure, or, granted that this is the case, how much of the protein is present in a given solution.

Type
Part I.—Original Articles
Copyright
Copyright © Royal College of Psychiatrists, 1924 

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