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Investigation of the Permeability of the Brain Membranes in Cases of Mental Disorder

Published online by Cambridge University Press:  19 February 2018

Herbert A. Strecker
Herbert A. Strecker*
Affiliation:
The Laboratories of the Joint Board of Research for Mental Diseases, City and University of Birmingham
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Extract

The structures which separate the blood from the cerebro-spinal fluid are of considerable importance in the physiology and patho logy of the brain, since they form a barrier which allows only certain substances to diffuse from the blood into the cerebro-spinal fluid. It has been found that the acute phases of certain mental and nervous diseases are associated with an alteration of the permeability of the brain membranes which form this barrier. Only recently, however, has there been any quantitative investigation of the relative dis tribution of substances in the blood and cerebro-spinal fluid; by means of this quantitative ratio the degree of deviation from the normal in various conditions of disease can be readily determined.

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 74 , Issue 304 , January 1928 , pp. 73 - 80
Copyright
Copyright © Royal College of Psychiatrists, 1928 

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