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The Ætiology of the Confusional Syndrome and the Use of T.A.B. Vaccine

Published online by Cambridge University Press:  19 February 2018

D. N. Parfitt
D. N. Parfitt*
Affiliation:
Medical Superintendent, Warwickshire and Coventry Mental Hospital, Hatton
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Extract

Since the discovery that Bacillus coli vaccine (1) or albumose (2) were as effective as typhoid vaccine (3) in the treatment of typhoid fever, the use of non-specific protein therapy has been popular for almost any disease for which there is no other satisfactory form of treatment. T.A.B. vaccine, a mixture of typhoid and paratyphoid A and B organisms, has been found more regular and reliable in its results than typhoid vaccine (4); but milk, antitoxic sera, peptone and a variety of other substances have been used, and even malaria is considered a form of this treatment, segmentation of the parasites producing the foreign protein (5). It has been observed that Gram-negative organisms, such as the gonococcus and typhoid bacillus, produce more marked reactions when given intravenously than the Gram-positive organisms, such as staphylococci, streptococci and pneumococci (5).

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 84 , Issue 350-351 , May 1938 , pp. 563 - 573
Copyright
Copyright © Royal College of Psychiatrists, 1938 

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