Hostname: page-component-7c8c6479df-24hb2 Total loading time: 0 Render date: 2024-03-29T15:47:29.635Z Has data issue: false hasContentIssue false

Vitamin C in Senile Psychoses

A Preliminary Report

Published online by Cambridge University Press:  08 February 2018

P. Berkenau*
Affiliation:
The Warneford Hospital, Oxford

Extract

The senile psychoses are in regard to their origin an unsolved problem. Much valid work has been done in the field of anatomy and histology in approaching this problem, but as the mental diseases of old age cannot be separated from the growing old of body and mind generally, this problem is more or less a biological one. The borderline between old age and senile dementia is not a sharp one. In brains of old people without clinical symptoms of dementia there have been found histological changes, such as are usually found in cases of senile dementia. This makes it probable that the extent of degeneration of brain cells alone is not decisive for the appearance of senile psychoses. The finding of the characteristic plaques in the brain of senile psychoses may give evidence of the extent of the process and the severity of clinical symptoms, but it does not tell us anything about their nature and origin. Whether a constitutional factor is decisive or whether the histological changes are a reaction to an unknown noxa is undecided. Heredity may have its share too.

Type
Part I.—Original Articles
Copyright
Copyright © Royal College of Psychiatrists, 1940 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Abt, H. L., Chinn, H., and Farmer, Ch. I. (1939), Amer. Journ. Med. Sci., 197, 229.CrossRefGoogle Scholar
Brieger, H., and Wachholder, K. (1940), Pflüger's Arch. Phys., 243, 206.CrossRefGoogle Scholar
Farmer, Ch. I., and Abt, H. L. (1935), Proc. Soc. Exp. Biol and Med. Google Scholar
Gordon, E. S., Severinghaus, E. L., and Stark, M. E. (1938), Endocrinology, 22, 45.CrossRefGoogle Scholar
Gosh, I., and Rokshil, P. C. (1936), Biochem. Z., 282, 223.Google Scholar
Goth, A. (1938), Z. f. Vit.-Forsch., 7, 326.Google Scholar
Govern, Th. M., Gaunda, F., and Wright, I. S. (1939), Amer. Journ. Med. Sci., 197, 310.Google Scholar
Harris, Roy, and Ward, (1933), Biochem. Journ., 27, 2011.CrossRefGoogle Scholar
Harris, and Roy, (1935), Lancet, i, 71.CrossRefGoogle Scholar
Hinzberg, K. (1937), Biochem. Z., 290, 125.Google Scholar
Hirata, Yoshito, and Suzuki, Kazuo (1937), Klin. Wochenschr., 20, 1019.CrossRefGoogle Scholar
Jezler, A., and Niederberger, (1936), ibid., 30, 710.Google Scholar
Kreuzwendedich van den Borne, G. A. (1939), Acta Med. Scand., 99, 449.Google Scholar
Melka, I., and Klimo, Z. (1938), Klin. Wochenschr., 302.Google Scholar
Monauni, (1937), Z. Neur., 157, 636.Google Scholar
Neuweiler, W. (1938), Z. f. Vit.-Forsch., 7, 128.Google Scholar
Plaut, F., and Bulow, M. (1934 and 1938), Klin. Wochenschr., 1744.CrossRefGoogle Scholar
Stoeger, K. (1939), Wien. klin. Wochenschr., 46, 1421.Google Scholar
Wachholder, K. (1934). Deutsch. med. Wochenschr., 33, 1140.Google Scholar
Idem (1936), Hoppe-Seyler Z., 289, 149.Google Scholar
Idem and Hamel, P. (1937), Klin. Wochenschr., 1, 1740.Google Scholar
Wortis, H., Liebmann, I., and Wortis, B. (1938), Amer. Journ. Med. Sci., 196, 384.CrossRefGoogle Scholar
Youmans, I. B., Corletty, M. B., Ackeroid, I. H., and Frank, H. (1936), Amer. Journ. Med. Sci., 191, 319.CrossRefGoogle Scholar
Zilva, S. S., and Kellie, A. E. (1939). Biochem. J., 153 Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.