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The Occurrence and Significance of Small Vascular Lesions in the Brain

Published online by Cambridge University Press:  08 February 2018

F. A. Pickworth
F. A. Pickworth*
Affiliation:
Department of Mental Disease Research, University of Birmingham
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Extract

The haemorespiratory system is subject to disease like any other tissue of the body. Degenerative changes of large arteries are known to have occurred thousands of years ago, and atherosclerosis is to be found throughout the world irrespective of race or geographical distribution. The first recorded observations of disease of the cerebral vessels appeared in the year 1700 (1). Perivascular softenings were noted in 1814 (2); a book on disease of the brain with clinical associations was published in 1836 (3). Atheroma was studied in 1844 (4), and periarteritis of the cerebral vessels in 1868 (5) and 1887 (6). Changes in the vessel walls and perivascular cells were noted in 1863 (7), and white cells and emboli seen in cerebral vessels in 1882 (8).

Type
Part I.—Original Articles
Information
Journal of Mental Science , Volume 87 , Issue 366 , January 1941 , pp. 50 - 76
Copyright
Copyright © Royal College of Psychiatrists, 1941 

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