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The Galactose Tolerance Test in Phenylketonuria
Published online by Cambridge University Press: 08 February 2018
Extract
In cases where there is known to be a disturbance of metabolism it is natural to speculate upon the possible site of dysfunction in the organs and tissues of the body.
In phenylketonuria the basic biochemical error is a disordered metabolism of phenylalanine, the patient being unable to dispose of this substance at a normal rate (Jervis et al., 1940). The phenylpyruvic acid in the urine of phenylketonuric patients is derived from a deamination of phenylalanine in the kidney.
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- Part I.—Original Articles
- Information
- Copyright
- Copyright © Royal College of Psychiatrists, 1950
References
Coquet, M., Myle, G., Nyssen, R., Van Bogaert, L. (1944), Monatsschrift fur Psychiatrie, 109, 133.Google Scholar
Delay, J., Pichot, P., Desgrez, P., and Delbarre, F. (1947), “L'Oligophrénie phenylpyruvique,” Scm. Hop. Paris, 23, 1749–58.Google Scholar
Jervis, , Block, , Bolling, and Kanze, (1940), “Chemical and metabolic studies on phenylalanine,” J. Biol. Chem., 134, 105–113.CrossRefGoogle Scholar
Penrose, L. S. (1939), “Peripheral nerve tumours in a case of phenylketonuria,” Lancet, i, 572.CrossRefGoogle Scholar
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