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Phenylpyruvic Oligophrenia

Published online by Cambridge University Press:  08 February 2018

Valerie Cowie*
Affiliation:
Fountain Hospital, Tooting, S.W. 7

Extract

“The study of phenylpyruvic amentia may throw light on the whole problem of mental deficiency.”—Jervis.

Phenylpyruvic oligophrenia is a syndrome in which mental deficiency is accompanied by the excretion of phenylpyruvic acid in the urine.

Type
Part I.—Original Articles
Copyright
Copyright © Royal College of Psychiatrists, 1951 

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References

Bates, R. M., “Three Cases of Phenylpyruvic Oligophrenia,” J. Ment. Sci., 1938, 85, 273.Google Scholar
Block, R. J., Jervis, G. A., Bolling, D., and Webb, M., “Chemical and Metabolic Studies on Phenylalanine; Amino Acid Content of Tissue Proteins of Normal and Phenylpyruvic Oligophrenic Individuals,” J. Biol. Chem., 1940, 134, 567572.Google Scholar
Brugger, C., “Die Ausscheidung von Phenylbrenztraubensäure im Urin von Schwachsinnigen,” Schweiz. Arch. f. Neurol. u. Psychiat., 1942, 49, 6269.Google Scholar
Cowie, V. A., “The Galactose Tolerance Test in Phenylketonuria,” J. Ment. Sci., 1950, July.Google Scholar
Delay, J., Pichot, P., “Etude de quelques aspects biologiques de l'oligophrénie phénylpyruvique,” Ann. med. Psychol., 1947, ii, 6164.Google Scholar
Iidem, Desgrez, P., and Delbarre, F., “L'oligophrénie phénylpyruvique,” Bull. Mem. Soc. Med. Hâp. Paris, 1946, 62, 300302.Google Scholar
Iidem and Polonowski, M., “L'oligophrénie phénylpyruvique,” Sem. H⊚p. Paris, 1947, 23, 17491758.Google Scholar
Idem, Pichot, P., Delbarre, F., and Tasseel, J., “L'oligophrénie phénylpyruvique; nouvelles observations,” Bull. Mem. Soc. Med. H⊚p. Paris, 1948, 64, 669673.Google Scholar
Embden, G., and Baldes, K., Biochem. Z., 1913, 55, 301.Google Scholar
Föllings, A., “Utzkillelse av fenylpyroduesyre i urinen som stofskiftesanomali forbindelse med imbecilitet,” Nord. med. tideskr., 1934, 8, 1054.Google Scholar
Idem, Mohr, O. L., and Rund, L., “Oligophrenia Phenylpyrouvica; a Recessive Syndrome in Man,” Norske Videnskaps-Akad. i. Oslo Mat. Naturv. Klasse 1944, I945, 13.Google Scholar
Frazier, R. L., “Phenylpyruvic Amentia,” Am. J. Ment. Def., 1947, 51, 577586.Google Scholar
Gibbs, F. A., and Gibbs, E. L., “Phenylpyruvic Amentia,” Atlas of Electroencephalography, 1941.Google Scholar
Himwich, H. E., and Fazekas, J. F., “Cerebral Metabolism in Mongolian Idiocy and Phenylpyruvic Oligophrenia,” Arch. Neurol. Psychiat., 1940, 44, 12131218.Google Scholar
Jervis, G. A., “Inherited Biochemical Alterations in Certain Types of Mental Deficiency,” Proc. Am. Assoc. Ment. Def., 1937a, 61, 101115.Google Scholar
Idem, “Phenylpyruvic Oligophrenia; Introductory Study of 50 Cases of Mental Deficiency Associated with Excretion of Phenylpyruvic Acid,” Arch. Neurol. Psychiat., 1937b, 38, 944963.Google Scholar
Idem, “Metabolic Investigations on Cases of Phenylpyruvic Oligophrenia,” J. Biol. Chem., 1938, 126, 305313.Google Scholar
Idem, “Genetics of Phenylpyruvic Oligophrenia : A Contribution to Study of Influence of Heredity on Mental Defect,” J. Ment. Sci., 1939, 85, 719762.Google Scholar
Idem, Block, R. J., Bolling, D., and Kanze, E., “Chemical and Metabolic Studies on Phenylalanine; Phenylalanine Content of Blood and Spinal Fluid in Phenylpyruvic Oligophrenia,” J. Biol. Chem., 1940, 134, 105113.Google Scholar
Idem. ibid., 1947, 169, 651.Google Scholar
Larcomb, J. M., “Phenylketonuria and the Congenitally Deaf,” J. Pediat., 1939, 14, 348.Google Scholar
Lepow, H., “Oligophrénie phénylpyruvique. Etude clinique et biologique,” Monatschr. f. Psychiat. u. Neurol., 1944, 110, 161.Google Scholar
Medes, G., Biochem. J., 1932, 26, 917.Google Scholar
Morel, F., “Récherches généalogiques sur un cas d'oligophrénie phénylpyruvique,” Arch. Jul. Klaus Stift., 1944, 19.Google Scholar
Munro, T. A., “Phenylketonuria : Data on Forty-seven British Families,” Ann. Eugenics, 1947, 14, 6688.Google Scholar
Idem, Penrose, L. S., and Taylor, G. L., “A Study of the Linkage Relationship between the Genes for Phenylketonuria and the ABO Allelomorphs in Man,” Proc. Seventh Int. Genet. Congre., 1939, C.U.P.Google Scholar
Idem, “The Genetics of Phenylketonuria,” ibid. Google Scholar
Myers, B., “Statistics … of 1,400 London Children,” Brit. J. Child Dis., 1926, 23, 87.Google Scholar
Myle, , Coquet, , Nyssen, and Van Bogaert, , “Deuxieme cas vérifié anatomiquement d'oligophrénie phenylpyruvique,” Monatschr. f. Psychiat. u. Neurol. 1944, 1944.Google Scholar
Myle, G., “L'oligophrénie phénylpyruvique ou maladie de Föllings,” Ann. Med. Psychol., 1945, 11.Google Scholar
Penrose, L. S., “Two Cases of Phenylpyruvic Amentia,” Lancet, 1935a, i, 23.Google Scholar
Idem, “Inheritance of Phenylpyruvic Amentia,” ibid., 1935b, ii, 192.Google Scholar
Idem and Quastel, J. H., “Metabolic Studies in Phenylketonuria,” Biochem. J., 1937, 31, 266.Google Scholar
Idem, “Peripheral Nerve Tumours in a Case of Phenylketonuria,” Lancet, 1939, i. 572.Google Scholar
Idem, “A Contribution to the Genetical Study of Phenylketonuria,” Trans. Roy. Soc. Canada, 1941, 35, Sec. (5), 81.Google Scholar
Idem, “Search for Linkage between ABO Agglutinogens and Phenylketonuria,” Am. J. Ment. Def., 1945, 50, 4.Google Scholar
Idem, “Phenylketonuria : A Problem in Eugenics,” Lancet, 1946, i, 949.Google Scholar
Idem, “Phenylketonuria,” The Biology of Mental Defect, 1949. Sidgwick & Jackson.Google Scholar
Idem and Cowie, , Ann. Eugenics, 1951, 15, 297.Google Scholar
Pichot, , Delay, , Bertagna, , “L'oligophrénie phénylpyruvique,” Extrait des Annales Médico-Psychologiques, no. 3, 1949.Google Scholar
Polonowski, M., Desgrez, P., and Delbarre, F., “Recherches sur l'oligophrénie phénylpyruvique. Methods de dosage de l'acide phénylpyruvique dans des urines,” Bull. Soc. Chim. Biol., 1947, 29, 10491054.Google Scholar
Rhein, M., and Stoeber, R., “Conservation des urines contenant de l'acide phénylpyruvique,” C. R. Mem. Soc. Biol., 1936, 3, 807.Google Scholar
Shay, H., Arch. Int. Med., 1931, 47, 391.Google Scholar
Turpin, R., and Duchene, H., “L'oligophrénie phénylpyruvique—resultat d'une enquête en France,” Sem. H⊚p. Paris, 1945, 21, 345348.Google Scholar
Turpin, R., Dagand, H., Duchene, H., and Delbarre, F., “Presentation clinique d'un malade atteint d'oligophrénie phénylpyruvique,” Ann. Med. Psychol., 1947, ii, 6567.Google Scholar
Williams, D., “New Orientations in Epilepsy,” Brit. Med. J., 1950, i, March 25, p. 685.Google Scholar
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