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Clinical, Biochemical and Physiological Studies in Cases of Recurrent Schizophrenia

Published online by Cambridge University Press:  08 February 2018

Donald W. Rowntree
Affiliation:
From the Department of Pathology of Mental Disease, Institute of Psychiatry, Maudsley Hospital, London
W. W. Kay
Affiliation:
Mental Hospitals Group Laboratory, South-West Metropolitan Hospital Region

Extract

During the clinical observation of a female patient suffering from recurrent schizophrenic attacks, it was noticed that each psychotic episode was associated with the appearance of acne, and also that during remissions the patient showed an unusual craving for salt. These observations, together with the automatic disturbances characteristic of the onset of attacks, suggested that the adrenal cortex might play a part in the metabolic changes in this type of case, particularly the changes in nitrogen balance which have been demonstrated by Gjessing (1932, 1938). The work here reported was therefore primarily concerned with investigating the possible relationship between adrenal cortex activity and nitrogen metabolism in two patients of this type.

Type
Part I.—Original Articles
Copyright
Copyright © Royal College of Psychiatrists, 1952 

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References

Altschule, M. D., and Tillotson, K. J., Am. J. Psychiat., 1949, 105, 829.Google Scholar
Ashby, W. R., J. Ment. Sci., 1949, 95, 275.CrossRefGoogle Scholar
Forsham, P. H., Thorn, G. W., Prunty, F. T. G., and Hills, A. G., J. Clin. Endocrinol., 1948, 8, 15.Google Scholar
Gellhorn, E., and Ballin, H. M., Am. J. Physiol., 1946, 146, 559.CrossRefGoogle Scholar
Gjessing, R., Arch. Psychiat., 1932, 96, 319.Google Scholar
Idem , J. Ment. Sci., 1938, 84, 608.Google Scholar
Guterman, H. S., and Schroeder, M. S., J. Lab. Clin. Med., 1948, 33, 356.Google Scholar
Harrison, G. A., Chemical Methods in Clinical Medicine, 3rd ed., 1947 (i), p. 389.Google Scholar
Idem , ibid., 1947 (ii), p. 373.Google Scholar
Idem , ibid., 1947 (iii), p. 346.Google Scholar
Idem , ibid., 1947 (iv), p. 96.Google Scholar
Idem , ibid., 1947 (v), p. 90.Google Scholar
Hawk, P. B., and Bergeim, O., Practical Physiological Chemistry, 11th ed., 1938, p. 768.Google Scholar
Idem , Oser, B. L., and Summerson, W. H., ibid., 12th ed., 1947, p. 839.Google Scholar
Hill, D., Fol. Psychiat., Neurol. Neerland., Congresnummer, 1948, p. 95.Google Scholar
Lewis, R. A., and Wilkins, L., J. Clin. Investig., 1949, 28, 394.CrossRefGoogle Scholar
Mason, H. L., and others, J. Clin. Endocrinol., 1948, 8, 1.CrossRefGoogle Scholar
McQuarrie, I., Anderson, J. A., and Zeigler, M. R., ibid., 1942, 2, 406.Google Scholar
Means, J. H., Lancet, 1949, 257, 543.CrossRefGoogle Scholar
Paterson, J., McPhee, I. M., and Greenwood, A. W., Brit. Med. J., 1942, i, 35.CrossRefGoogle Scholar
Schoenheimer, P., and Sherry, M., J. Biol. Chem., 1934, 166, 745.Google Scholar
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