Table 2

Morbidity before and during lithium maintenance

Measure Before During Reduction (%)
1.Mania in type I, hypomania in type II.
2.Hospitalisation rate refers to 178 (49.4%) patients with at least one hospitalisation before lithium treatment, which lasted an average of 7.13 ± 5.62 years in this subgroup. All paired t≥3.60; all P<0.0001.
Annual rates (mean (s.d.))
Episodes 1.83 (2.14) 0.81 (1.11) 55.7
Manias1 0.99 (1.48) 0.36 (0.53) 63.6
Depressions 0.84 (1.03) 0.45 (0.84) 46.4
Hospitalisations2 0.33 (0.86) 0.06 (0.22) 81.8
Morbidity (% of time (s.d.))
Total illness 45.7 (30.6) 19.9 (21.8) 56.5
Mania/hypomania 20.9 (22.3) 8.11 (12.8) 61.2
Depression 24.8 (22.5) 11.7 (16.7) 52.8
Episode duration (months (s.d.))
Mania/hypomania 3.14 (2.03) 2.53 (1.95) 19.4
Depression 4.84 (4.16) 3.27 (2.55) 32.4