Table 7

Historical trends in morbidity during lithium maintenance treatment

Decade n Percentage time ill (s.d.)1 Episodes/year (s.d.)2 Episode-free3 (%)
1.Percentage of time ill during treatment: F[2; 357 d.f.]=0.27, not significant (NS).
2.Episodes/year during treatment: F[2; 357 d.f.]=0.28, NS.
3.Proportion of patients with no recurrences during treatment: χ 2 [2 d.f.]=4.03, NS.
1970s 90 16.4 (20.4) 0.860 (1.102) 25.6
1980s 148 18.3 (21.4) 0.829 (1.138) 31.8
1990s 122 18.3 (23.3) 0.751 (1.126) 38.5
Total 360 17.8 (21.8) 0.810 (1.123) 32.5