Table 1

Required sample size per arm for various admission rates (assuming a 30% drop-out rate)

Admission rate (lithium) Admission rate (valproate)
0.15 0.20 0.25 0.30 0.35 0.40 0.45 0.50
0.20 1353 1746 483 236 145 101 76
0.25 391 1746 2092 565 271 162 111
0.30 196 483 2092 2381 631 296 175
0.40 88 145 271 631 2608 2769 713
0.50 55 76 111 175 315 713 2869