Table 2

Overview of reasons for discontinuation in intention-to-treat sample (% patients)

Primary reason Placebo (n=130) Venlafaxine ER
37.5 mg (n=140) 75 mg (n=134) 150 mg (n=137)
1.P<0.001 for venlafaxine ER compared with placebo.
2.Includes: failed to return, patient request, protocol violation, other medical or non-medical event.
Any reason 45 38 33 31
Unsatisfactory response/efficacy1 21 17 10 4
Adverse event 14 11 17 16
Other2 11 9 5 9