Table 5

Overview of week of onset of efficacy for intention-to-treat sample using the last observation carried forward method

Parameter Venlafaxine ER1
37.5 mg 75 mg 150 mg
HRSA, Hamilton Rating Scale for Anxiety; BSA, Brief Scale for Anxiety; HAD, Hospital Anxiety and Depression scale; CGI I, Clinical Global Impression of Improvement; CGI—S, Clinical Global Impression of Severity.
1.Significantly different from placebo in pairwise comparisons of venlafaxine ER commencing at the week indicated (P ≤ 0.05 on the F-test).
HRSA total score 2 2 2
BSA total score 3 3 2
HRSA psychic anxiety factor 2 2 2
BSA psychic anxiety factor 3 2 1
HRSA somatic anxiety factor 10 8 8
BSA somatic anxiety factor 4 4 4
HAD anxiety subscale 3 2 1
HAD depression subscale 3 3 3
HRSA anxious mood item 2 2 2
CGI—I 3 3 3
CGI—S 3 3 2