Table 7

Percentage of patients with discontinuation symptoms on the Benzodiazepine Withdrawal Symptom Questionnaire (Tyrer et al, 1990): ≥ 10% incidence and at least twice the incidence seen with placebo

Symptoms Placebo (n=71) Venlafaxine ER
37.5 mg (n=82) 75 mg (n=80) 150 mg (n=84)
Dizziness < 1 15 10 13
Light-headedness 4 15 8 12
Tinnitus < 1 2 4 13
Nausea 3 9 6 18
Vomiting < 1 5 3 12
Loss of appetite 3 6 4 10