Response | Partial response | Non-response | ||
---|---|---|---|---|

Statistics: | ||||

Test of interaction between the two treatment modalities: Wald χ
^{2}=0.88; P < 0.349 (based on ordinal logistic
regression model for group v. response, partial or non-response). | ||||

Sertraline groups v. non-sertraline groups: χ^{2}=12.53,
P < 0.001; odds ratio=0.534 (95% CI 0.347-0.835) | ||||

Exposure groups v. non-exposure groups: χ^{2}=2.18,
P=0.140; odds ratio=0.732 (95% CI 0.475-1.134) | ||||

Difference between all four groups: χ^{2}=15.73; P=0.0013 | ||||

Pairwise comparisons: | ||||

Sertraline/exposure v. placebo: χ^{2}=12.32, P < 0.001 | ||||

Sertraline/exposure v. exposure: χ^{2}=3.57,
P=0.059 | ||||

Sertraline/exposure v. sertraline: χ^{2}=0.22,
P=0.640 | ||||

Sertraline v. placebo: χ^{2}=10.13, P=0.002 | ||||

Sertraline v. exposure: χ^{2}=2.20, P=0.138 | ||||

Exposure v. placebo: χ^{2}=3.01, P=0.083 | ||||

Sertraline/exposure |
(n=88) | 40 (45.5%) | 21 (23.9%) | 27 (30.7%) |

Sertraline |
(n=87) | 35 (40.2%) | 25 (28.7%) | 27 (31.0%) |

Exposure/placebo |
(n=91) | 30 (33.0%) | 22 (24.2%) | 39 (42.9%) |

Placebo |
(n=88) | 21 (23.9%) | 18 (20.5%) | 49 (55.7%) |