Table 4

Risk of bipolar disorder for individuals scoring an A grade in each individual subject compared with a reference group of those scoring B–D, crude and fully adjusted

Crude Adjusteda
Subject Hazard ratio (95% CI) P Hazard ratio (95% CI) P
a. School subjects ordered by strength of association with bipolar disorder.
Childcare 2.18 (1.58-3.02) <0.001 1.95 (1.39-2.75) <0.001
Swedish 2.24 (1.59-3.15) <0.001 1.92 (1.34-2.76) <0.001
Geography 2.11 (1.52-2.95) <0.001 1.88 (1.34-2.66) <0.001
Music 2.05 (1.48-2.84) <0.001 1.77 (1.26-2.49) 0.001
Religion 2.00 (1.44-2.78) <0.001 1.75 (1.25-2.47) 0.001
Biology 2.12 (1.45-2.79) <0.001 1.68 (1.19-2.37) 0.003
History 1.83 (1.32-2.46) <0.001 1.58 (1.12-2.23) 0.009
Engineering 1.59 (0.96-2.63) 0.073 1.47 (0.88-2.45) 0.138
Civics 1.72 (1.22-2.43) 0.002 1.46 (1.02-2.10) 0.039
Home economics 1.68 (1.14-2.47) 0.008 1.46 (0.98-2.17) 0.064
English 1.60 (1.09-1.35) 0.017 1.35 (0.90-2.01) 0.145
Chemistry 1.52 (1.05-2.18) 0.025 1.34 (0.92-1.95) 0.128
Mathematics 1.44 (0.98-2.11) 0.064 1.32 (0.89-1.95) 0.169
Art 1.36 (0.92-2.02) 0.119 1.16 (0.77-1.73) 0.485
Physics 1.30 (0.89-1.91) 0.181 1.11 (0.74-1.65) 0.622
Handicraft 0.64 (0.36-1.15) 0.133 0.58 (0.33-1.04) 0.069
Sport 0.42 (0.24-0.75) 0.003 0.40 (0.23-0.72) 0.002