Table 1

Results of linear regression analyses of the continuous genetic risk score against the continuous age at menarche variable and confounders

Genetic risk score
VariablenEstimate (95% CI)P
Age at menarche (months)2772−0.42 (−0.49 to −0.35)1.410−28
Body mass index at age 92705  0.04 (0.02 to 0.05)2.010−5
Body mass index at age 152122  0.05 (0.03 to 0.07)2.010−5
Maternal antenatal depression2590  0.01 (−0.01 to 0.02)0.34
Maternal postnatal depression2684−0.002 (−0.02 to 0.01)0.80
Maternal age2709−0.02 (−0.06 to 0.02)0.30
Maternal education2745−0.001 (−0.01 to 0.00)0.81
Social class2645  1.010−14 (−0.01 to 0.01)0.98
Financial problems2704−0.003 (−0.01 to 0.00)0.20
Home ownership2922−0.004 (−0.02 to 0.01)0.56
Father absence2747  0.002 (0.00 to 0.01)0.15
Siblings, n2741  1.010−14 (0.00 to 0.00)0.85