Table 1

Studies meeting inclusion criteria examining lipid and adipocytokine parameters in first-episode schizophrenia and related disorders

SettingPatients
n
DSM diagnosesPatient age,
years: mean
(s.d.)
Control
group
n
Lipid
parameters
Antipsychotic
status
Patient BMI,
kg/m2: mean
(s.d)
Matching
Chen et al (2016)15China172Schizophrenia28.7 (9.9)31TC, LDL, HDL, TGAll naïve21.8 (3.8)BMI, age, ethnicity, gender,
smoking
Petrikis et al (2015)38Greece40Schizophrenia, schizophreniform,
brief psychotic episode
32.5 (9.8)40TC, HDL, TGAll naïve22.9 (3.7)BMI, age, gender, smoking
Srihari et al (2013)51USA76Schizophrenia, schizophreniform,
brief psychotic episode
22.4 (4.8)156TC, LDL, HDL, TG14 days' antipsychotic
use
25.0 (4.0)Age, gender, ethnicity
Enez Darcin et al (2015)39Turkey40Schizophrenia34.6 (1.1)70HDL, TGAll naïve24.3 (7.4)BMI, age, smoking
Dasgupta et al (2010)40India30Schizophrenia32.5 (10.5)25TC, LDL, HDL, TGAll naïve21.0 (3.1)BMI, age, ethnicity, diet, gender
Arranz et al (2004)41Spain50Schizophrenia25.2 (0.6)50LeptinAll naïve22.2 (2.1)BMI, gender
Ryan et al (2003)18UK/Ireland26Schizophrenia33.6 (13.5)26TC, LDL, HDL, TGAll naïve24.5 (3.6)BMI, age, gender, smoking,
diet, exercise
Basoglu et al2010)42Turkey27Schizophrenia21.2 (0.8)22LDL, HDL, TG, leptinAll naïve22.0 (2.2)Age, gender, smoking, BMI
Kirkpatrick et al (2010)43Spain87Schizophrenia, schizophreniform
disorder, brief psychotic disorder,
psychosis NOS
27.1 (5.3)92TC, LDL, HDL, TG<7 days' antipsychotic
use
22.3 (3.8)Age, gender, smoking, BMI
Spelman et al (2007)44Ireland38Schizophrenia25.2 (5.6)38TC, LDL, HDL, TG, leptinAll naïve22.8 (3.1)Age, gender, smoking ethnicity
Wang et al (2007)45Taiwan16Schizophrenia25.2 (4.9)16LeptinAll naïve22.3 (3.9)Age, gender, BMI
Saddichha et al (2008)19India99Schizophrenia26.0 (5.5)51HDL, TGAll naïveNSAge, gender, diet, exercise
Sengupta et al (2008)46Canada38Schizophrenia spectrum disorder25.4 (5.6)36TC, LDL, HDL, TG<10 days' antipsychotic
use
22.8 (3.2)BMI, age, gender, ethnicity
Venkatasubramanian et al (2010)47India38Schizophrenia32.2 (7.6)38TC, TG, leptinAll naïve20.0 (3.1)BMI, age, gender,
socio-economic status
Chen et al (2016)16China60Schizophrenia28.2 (10)28TC, TG<14 days' antipsychotic
use
21.9(3.8)BMI, age, gender, smoking
Wu et al (2013)48China70Schizophrenia24.5 (7)44TC, LDL, HDL, TGAll naïve19.6 (2.5)BMI, age, gender, ethnicity
Verma et al (2009)17Singapore160Schizophrenia spectrum disorder,
affective psychosis, psychosis NOS,
other psychotic disorders
30.0 (6.5)200TC, LDL, HDL<3 days' total
antipsychotic use
21.2 (3.7)Age, gender, ethnicity
Misiak et al (2016)20Poland24Schizophrenia26.8 (2.9)146TC, LDL, HDL, TGAll naïve23.0 (2.9)Age, gender, BMI
Sarandol et al (2015)50Turkey26At 6 months a DSM diagnosis of
schizophrenia/bipolar affective
disorder was made
25.6 (7.0)25TC, LDL, HDL, TGAll naïve22.0 (3.3)Age, gender, BMI, smoking
Kavzoglu et al (2013)49Turkey50Schizophrenia30.1 (7.5)50TC, HDL, LDL, TGAll naïveNSAge, gender, BMI, smoking
  • BMI, body mass index; HDL, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; NOS, not otherwise specifed. TC, total cholesterol; TG, triglyceride.